| SP | deGrom, J.deGrom, Jacob $$ >> | 33 | 2021 | R | 100 | 21 | 21 | 7 | 10 | 4.24 | .297 | 1.23 | 8.7 | 2.5 | 9.1 | 131.2 | 126 | 63 | 62 | 15 | 36 | 132 | 0 | 0 | 0 | 0 | 13 | 5 | 0 | 3.41 |
| SP | Cole, G.Cole, Gerrit $ >> | 28 | 2019 | R | 91 | 20 | 20 | 5 | 9 | 5.57 | .338 | 1.52 | 10.3 | 3.5 | 8.8 | 108.1 | 123 | 67 | 67 | 18 | 42 | 106 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 4.40 |
| SP | Nelson, R.Nelson, Roger $ >> | 28 | 1972 | R | 84 | 20 | 20 | 2 | 13 | 6.36 | .353 | 1.63 | 10.9 | 3.8 | 5.0 | 93.1 | 113 | 71 | 66 | 14 | 39 | 52 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 5.13 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 19 | 19 | 6 | 7 | 6.35 | .366 | 1.70 | 11.5 | 3.9 | 7.2 | 106.1 | 135 | 78 | 75 | 14 | 46 | 85 | 0 | 0 | 0 | 0 | 7 | 3 | 0 | 4.50 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 38 | 0 | 4 | 2 | 1.69 | .262 | 1.02 | 6.4 | 2.8 | 8.6 | 48.0 | 34 | 10 | 9 | 3 | 15 | 46 | 0 | 17 | 4 | 0 | 0 | 2 | 1 | 2.96 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 48 | 0 | 4 | 3 | 5.46 | .331 | 1.43 | 9.0 | 4.0 | 7.6 | 59.1 | 59 | 40 | 36 | 9 | 26 | 50 | 0 | 0 | 1 | 0 | 0 | 3 | 2 | 4.76 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 46 | 0 | 1 | 4 | 5.13 | .333 | 1.48 | 7.1 | 6.4 | 9.2 | 52.2 | 41 | 30 | 30 | 9 | 37 | 53 | 0 | 1 | 1 | 0 | 0 | 1 | 9 | 5.40 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 45 | 0 | 2 | 1 | 3.29 | .271 | 1.12 | 6.8 | 3.3 | 3.6 | 52.0 | 39 | 25 | 19 | 4 | 19 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.29 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 19 | 1 | 1 | 1 | 5.44 | .342 | 1.52 | 10.1 | 3.7 | 5.8 | 82.2 | 92 | 56 | 50 | 14 | 34 | 53 | 0 | 0 | 0 | 0 | 1 | 3 | 2 | 5.28 |