| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 29 | 29 | 15 | 8 | 2.80 | .250 | 0.98 | 6.7 | 2.2 | 7.6 | 196.1 | 145 | 62 | 61 | 12 | 48 | 165 | 2 | 0 | 0 | 1 | 23 | 3 | 2 | 2.89 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 28 | 28 | 17 | 2 | 2.85 | .286 | 1.18 | 6.5 | 4.2 | 5.4 | 189.1 | 136 | 63 | 60 | 12 | 88 | 114 | 1 | 0 | 0 | 0 | 22 | 3 | 3 | 4.06 |
| SP | Mathewson, C.Mathewson, Christy † $ >> | 29 | 1909 | R | 86 | 28 | 28 | 14 | 8 | 3.48 | .311 | 1.34 | 9.4 | 2.7 | 5.0 | 230.1 | 241 | 102 | 89 | 18 | 68 | 128 | 15 | 0 | 0 | 1 | 17 | 3 | 2 | 3.83 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 26 | 26 | 19 | 4 | 4.01 | .305 | 1.30 | 9.0 | 2.7 | 4.5 | 213.1 | 214 | 100 | 95 | 21 | 63 | 107 | 11 | 0 | 0 | 0 | 14 | 4 | 4 | 4.22 |
| RP | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 69 | 0 | 6 | 3 | 2.90 | .242 | 0.93 | 6.1 | 2.4 | 9.0 | 83.2 | 56 | 27 | 27 | 7 | 22 | 83 | 0 | 16 | 4 | 0 | 0 | 2 | 0 | 2.96 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 28 | 0 | 4 | 4 | 4.13 | .292 | 1.20 | 6.4 | 4.5 | 7.7 | 28.1 | 20 | 15 | 13 | 2 | 14 | 24 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 3.82 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 13 | 0 | 0 | 0 | 5.40 | .340 | 1.46 | 12.3 | 1.6 | 6.5 | 11.2 | 15 | 10 | 7 | 1 | 2 | 8 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 3.55 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 17 | 0 | 3 | 0 | 3.23 | .259 | 1.05 | 6.7 | 2.8 | 7.8 | 39.0 | 29 | 14 | 14 | 3 | 12 | 34 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 3.18 |