| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 21 | 21 | 9 | 8 | 5.22 | .312 | 1.33 | 10.0 | 2.0 | 8.6 | 141.1 | 156 | 92 | 82 | 27 | 32 | 134 | 1 | 0 | 0 | 1 | 11 | 4 | 3 | 4.35 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 20 | 20 | 8 | 5 | 3.86 | .332 | 1.47 | 8.8 | 4.4 | 5.9 | 126.0 | 123 | 55 | 54 | 13 | 62 | 82 | 0 | 0 | 0 | 0 | 11 | 3 | 2 | 4.59 |
| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 95 | 19 | 19 | 9 | 4 | 3.88 | .309 | 1.32 | 8.4 | 3.5 | 9.1 | 125.1 | 116 | 64 | 54 | 13 | 49 | 127 | 0 | 0 | 0 | 0 | 11 | 3 | 0 | 3.57 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 76 | 20 | 19 | 10 | 6 | 3.46 | .263 | 1.05 | 8.2 | 1.3 | 4.8 | 150.2 | 136 | 65 | 58 | 20 | 22 | 80 | 7 | 0 | 0 | 0 | 11 | 3 | 0 | 4.17 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 35 | 0 | 2 | 3 | 4.30 | .289 | 1.22 | 7.8 | 3.4 | 9.2 | 37.2 | 32 | 19 | 18 | 6 | 14 | 38 | 0 | 3 | 5 | 0 | 0 | 0 | 0 | 4.19 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 46 | 0 | 3 | 2 | 3.67 | .259 | 1.05 | 7.9 | 1.6 | 8.2 | 34.1 | 30 | 16 | 14 | 7 | 6 | 31 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 4.38 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 27 | 0 | 1 | 2 | 2.52 | .279 | 1.16 | 7.6 | 2.9 | 11.5 | 25.0 | 21 | 7 | 7 | 1 | 8 | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1.92 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 57 | 0 | 1 | 0 | 3.72 | .271 | 1.10 | 6.6 | 3.4 | 8.8 | 48.1 | 35 | 20 | 20 | 8 | 18 | 47 | 0 | 1 | 1 | 0 | 0 | 1 | 6 | 4.40 |