| SP | Verlander, J.Verlander, Justin $ >> | 36 | 2019 | R | 99 | 19 | 19 | 7 | 9 | 4.42 | .310 | 1.32 | 7.7 | 4.1 | 8.1 | 114.0 | 98 | 57 | 56 | 18 | 52 | 102 | 1 | 0 | 0 | 0 | 10 | 4 | 4 | 4.74 |
| SP | Santana, J.Santana, Johan $ >> | 25 | 2004 | L | 91 | 18 | 18 | 6 | 6 | 4.39 | .326 | 1.44 | 10.0 | 3.0 | 10.6 | 108.2 | 120 | 53 | 53 | 20 | 36 | 127 | 0 | 0 | 0 | 0 | 12 | 2 | 1 | 4.11 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 84 | 18 | 18 | 8 | 9 | 4.47 | .317 | 1.36 | 8.9 | 3.4 | 7.8 | 100.2 | 99 | 56 | 50 | 10 | 38 | 87 | 0 | 0 | 0 | 0 | 7 | 3 | 3 | 3.79 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 72 | 19 | 18 | 5 | 10 | 7.95 | .375 | 1.74 | 12.3 | 3.4 | 6.2 | 94.0 | 128 | 86 | 83 | 21 | 36 | 65 | 3 | 0 | 0 | 0 | 5 | 5 | 4 | 5.83 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 29 | 0 | 1 | 3 | 1.99 | .258 | 0.98 | 7.0 | 2.0 | 11.9 | 31.2 | 24 | 12 | 7 | 3 | 7 | 41 | 0 | 11 | 1 | 0 | 0 | 2 | 0 | 2.48 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 37 | 0 | 0 | 1 | 4.93 | .297 | 1.20 | 7.8 | 3.2 | 10.4 | 45.2 | 39 | 29 | 25 | 10 | 16 | 52 | 0 | 1 | 3 | 0 | 0 | 3 | 0 | 4.84 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 49 | 0 | 2 | 2 | 6.25 | .353 | 1.61 | 9.5 | 5.2 | 13.1 | 40.1 | 42 | 28 | 28 | 7 | 23 | 58 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.18 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 76 | 35 | 0 | 2 | 2 | 5.29 | .315 | 1.35 | 8.5 | 3.7 | 10.1 | 34.0 | 32 | 20 | 20 | 6 | 14 | 38 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 4.38 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 65 | 17 | 0 | 3 | 1 | 4.66 | .298 | 1.26 | 8.6 | 2.8 | 8.5 | 75.1 | 72 | 39 | 39 | 11 | 23 | 71 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.97 |