| SP | Verlander, J.Verlander, Justin $$ >> | 36 | 2019 | R | 99 | 34 | 34 | 10 | 17 | 4.69 | .317 | 1.39 | 8.9 | 3.6 | 9.1 | 215.0 | 213 | 119 | 112 | 30 | 86 | 218 | 1 | 0 | 0 | 0 | 16 | 0 | 8 | 3.99 |
| SP | Santana, J.Santana, Johan $$ >> | 25 | 2004 | L | 91 | 33 | 33 | 13 | 14 | 4.91 | .338 | 1.51 | 9.3 | 4.4 | 8.3 | 194.1 | 200 | 109 | 106 | 36 | 94 | 178 | 2 | 0 | 0 | 0 | 17 | 3 | 3 | 5.08 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 82 | 32 | 32 | 8 | 12 | 5.39 | .341 | 1.54 | 9.6 | 4.2 | 9.2 | 167.0 | 179 | 103 | 100 | 27 | 78 | 171 | 0 | 0 | 0 | 0 | 13 | 2 | 1 | 4.49 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 32 | 32 | 12 | 11 | 5.18 | .324 | 1.42 | 9.5 | 3.2 | 7.1 | 184.0 | 195 | 108 | 106 | 29 | 66 | 145 | 1 | 0 | 0 | 1 | 16 | 4 | 8 | 4.61 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 68 | 31 | 31 | 8 | 15 | 5.46 | .340 | 1.52 | 10.6 | 3.0 | 5.8 | 191.1 | 226 | 124 | 116 | 26 | 64 | 123 | 8 | 0 | 0 | 1 | 14 | 6 | 7 | 4.58 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 55 | 0 | 4 | 7 | 3.45 | .333 | 1.48 | 8.2 | 5.2 | 11.4 | 57.1 | 52 | 26 | 22 | 7 | 33 | 72 | 0 | 33 | 3 | 0 | 0 | 1 | 1 | 3.86 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 90 | 58 | 0 | 1 | 2 | 4.38 | .263 | 1.04 | 6.6 | 2.8 | 11.4 | 72.0 | 53 | 35 | 35 | 9 | 22 | 91 | 0 | 2 | 7 | 0 | 0 | 2 | 0 | 3.10 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 86 | 0 | 6 | 2 | 2.70 | .255 | 1.03 | 6.3 | 3.0 | 10.7 | 93.1 | 65 | 36 | 28 | 7 | 31 | 111 | 0 | 1 | 7 | 0 | 0 | 0 | 1 | 2.59 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 63 | 0 | 2 | 4 | 5.29 | .308 | 1.31 | 9.0 | 2.8 | 11.0 | 68.0 | 68 | 41 | 40 | 12 | 21 | 83 | 0 | 3 | 1 | 0 | 0 | 2 | 2 | 3.87 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 49 | 0 | 3 | 0 | 4.71 | .313 | 1.37 | 9.0 | 3.5 | 9.9 | 49.2 | 49 | 26 | 26 | 9 | 19 | 54 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.35 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 35 | 0 | 3 | 2 | 4.00 | .274 | 1.13 | 8.2 | 2.0 | 9.2 | 45.0 | 41 | 20 | 20 | 8 | 10 | 46 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.93 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 27 | 0 | 4 | 2 | 4.95 | .324 | 1.38 | 8.5 | 4.0 | 9.8 | 107.1 | 101 | 62 | 59 | 19 | 47 | 117 | 0 | 0 | 0 | 0 | 0 | 6 | 3 | 4.61 |