| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 12 | 12 | 6 | 2 | 3.42 | .279 | 1.16 | 8.0 | 2.5 | 8.0 | 84.1 | 75 | 34 | 32 | 6 | 23 | 75 | 3 | 0 | 0 | 1 | 7 | 0 | 1 | 2.96 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 12 | 12 | 6 | 3 | 4.03 | .283 | 1.17 | 7.9 | 2.7 | 4.8 | 80.1 | 70 | 36 | 36 | 8 | 24 | 43 | 3 | 0 | 0 | 1 | 8 | 1 | 0 | 4.16 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 34 | 0 | 2 | 0 | 2.12 | .226 | 0.88 | 5.3 | 2.8 | 9.9 | 29.2 | 17 | 8 | 7 | 0 | 9 | 32 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1.72 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 18 | 0 | 2 | 1 | 2.45 | .267 | 1.04 | 6.0 | 3.5 | 8.5 | 18.1 | 12 | 5 | 5 | 2 | 7 | 17 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.89 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 11 | 0 | 1 | 1 | 4.32 | .359 | 1.68 | 6.8 | 9.0 | 10.1 | 8.1 | 6 | 6 | 4 | 2 | 8 | 9 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 7.00 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 9 | 0 | 0 | 0 | 3.72 | .237 | 0.93 | 6.0 | 3.0 | 8.0 | 9.2 | 6 | 4 | 4 | 1 | 3 | 8 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 7 | 1 | 1 | 0 | 3.52 | .330 | 1.43 | 9.0 | 3.9 | 5.1 | 23.0 | 23 | 9 | 9 | 0 | 10 | 13 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 3.30 |