| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 18 | 18 | 5 | 8 | 3.51 | .288 | 1.20 | 8.4 | 2.4 | 7.8 | 123.0 | 115 | 52 | 48 | 11 | 33 | 107 | 1 | 0 | 0 | 1 | 13 | 1 | 4 | 3.25 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 17 | 17 | 7 | 7 | 4.94 | .337 | 1.52 | 9.6 | 4.0 | 7.7 | 98.1 | 105 | 56 | 54 | 11 | 44 | 84 | 2 | 0 | 0 | 1 | 9 | 1 | 0 | 4.12 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 17 | 17 | 7 | 4 | 4.33 | .332 | 1.47 | 8.9 | 4.3 | 6.1 | 106.0 | 105 | 54 | 51 | 8 | 51 | 72 | 5 | 0 | 0 | 3 | 9 | 2 | 1 | 4.12 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 67 | 17 | 17 | 7 | 2 | 3.70 | .323 | 1.39 | 9.1 | 3.4 | 5.8 | 121.2 | 123 | 53 | 50 | 12 | 46 | 78 | 7 | 0 | 0 | 2 | 8 | 5 | 3 | 4.26 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 24 | 0 | 1 | 4 | 6.00 | .302 | 1.30 | 8.0 | 3.7 | 12.7 | 27.0 | 24 | 18 | 18 | 6 | 11 | 38 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.30 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 20 | 0 | 1 | 1 | 9.00 | .424 | 2.21 | 14.2 | 5.7 | 8.5 | 19.0 | 30 | 21 | 19 | 4 | 12 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.74 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 24 | 0 | 1 | 1 | 4.24 | .314 | 1.37 | 7.8 | 4.7 | 9.4 | 23.1 | 20 | 11 | 11 | 3 | 12 | 24 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.17 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 13 | 0 | 1 | 0 | 5.69 | .366 | 1.70 | 11.6 | 3.8 | 4.3 | 55.1 | 71 | 41 | 35 | 9 | 23 | 26 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.55 |