| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 27 | 27 | 8 | 9 | 4.11 | .295 | 1.23 | 8.3 | 2.8 | 5.8 | 190.1 | 175 | 89 | 87 | 21 | 60 | 122 | 2 | 0 | 0 | 1 | 18 | 4 | 1 | 4.16 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 26 | 26 | 8 | 13 | 3.73 | .308 | 1.31 | 7.5 | 4.4 | 4.5 | 169.0 | 140 | 93 | 70 | 17 | 82 | 85 | 2 | 0 | 0 | 1 | 15 | 4 | 1 | 4.83 |
| SP | Cueto, J.Cueto, Johnny † # >> | 28 | 2014 | R | 75 | 26 | 26 | 15 | 4 | 3.45 | .291 | 1.22 | 8.3 | 2.7 | 7.6 | 188.0 | 173 | 82 | 72 | 25 | 56 | 158 | 4 | 0 | 0 | 1 | 15 | 3 | 6 | 3.99 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 25 | 25 | 11 | 12 | 4.64 | .322 | 1.42 | 9.5 | 3.2 | 5.8 | 159.0 | 168 | 92 | 82 | 21 | 57 | 102 | 1 | 0 | 0 | 0 | 11 | 2 | 2 | 4.55 |
| SU | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 55 | 0 | 3 | 1 | 3.93 | .321 | 1.36 | 8.8 | 3.4 | 9.5 | 55.0 | 54 | 28 | 24 | 6 | 21 | 58 | 0 | 3 | 7 | 0 | 0 | 3 | 1 | 3.62 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 69 | 0 | 2 | 1 | 3.89 | .281 | 1.15 | 7.4 | 2.9 | 9.9 | 81.0 | 67 | 35 | 35 | 8 | 26 | 89 | 0 | 2 | 2 | 0 | 0 | 2 | 4 | 3.12 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 43 | 0 | 5 | 1 | 5.03 | .355 | 1.63 | 8.5 | 6.2 | 7.4 | 39.1 | 37 | 22 | 22 | 6 | 27 | 32 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 5.51 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 29 | 0 | 1 | 0 | 2.37 | .283 | 1.19 | 5.4 | 5.4 | 9.0 | 30.1 | 18 | 8 | 8 | 3 | 18 | 30 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.10 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 21 | 0 | 1 | 0 | 1.73 | .284 | 1.19 | 5.9 | 4.8 | 6.9 | 26.0 | 17 | 6 | 5 | 1 | 14 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.58 |