| SP | Arrieta, J.Arrieta, Jake $ >> | 29 | 2015 | R | 93 | 19 | 19 | 7 | 9 | 2.62 | .269 | 1.07 | 6.7 | 2.9 | 6.5 | 127.0 | 95 | 40 | 37 | 10 | 41 | 92 | 1 | 0 | 0 | 0 | 14 | 4 | 2 | 3.64 |
| SP | Mathewson, C.Mathewson, Christy † >> | 29 | 1909 | R | 85 | 18 | 18 | 12 | 4 | 3.06 | .258 | 1.02 | 7.1 | 2.1 | 4.5 | 126.1 | 100 | 47 | 43 | 8 | 29 | 63 | 4 | 0 | 0 | 1 | 12 | 3 | 1 | 3.59 |
| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 90 | 17 | 17 | 10 | 3 | 2.97 | .280 | 1.15 | 6.6 | 3.7 | 6.8 | 118.1 | 87 | 42 | 39 | 9 | 49 | 89 | 1 | 0 | 0 | 1 | 11 | 2 | 0 | 3.78 |
| SP | McDowell, S.McDowell, Sam # >> | 26 | 1968 | L | 45 | 16 | 16 | 7 | 3 | 4.05 | .287 | 1.19 | 7.4 | 3.4 | 6.3 | 106.2 | 87 | 48 | 48 | 13 | 40 | 74 | 2 | 0 | 0 | 1 | 9 | 2 | 4 | 4.39 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 20 | 0 | 1 | 2 | 2.66 | .208 | 0.79 | 5.9 | 1.4 | 8.1 | 20.1 | 13 | 6 | 6 | 2 | 3 | 18 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 2.95 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 9 | 0 | 0 | 0 | 2.45 | .313 | 1.36 | 10.6 | 1.6 | 9.0 | 11.0 | 13 | 3 | 3 | 2 | 2 | 11 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.91 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 4 | 0 | 0 | 0 | 3.18 | .346 | 1.59 | 7.2 | 9.0 | 9.0 | 5.2 | 4 | 2 | 2 | 0 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 3 | 0 | 0 | 0 | 3.86 | .222 | 0.86 | 4.5 | 4.5 | 18.0 | 4.2 | 2 | 2 | 2 | 1 | 2 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.75 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 13 | 0 | 0 | 0 | 5.32 | .365 | 1.68 | 9.8 | 5.3 | 10.2 | 22.0 | 24 | 13 | 13 | 3 | 13 | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.41 |