| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 17 | 17 | 7 | 5 | 4.31 | .301 | 1.28 | 8.8 | 2.7 | 3.3 | 119.0 | 116 | 62 | 57 | 15 | 36 | 43 | 4 | 0 | 0 | 1 | 6 | 2 | 0 | 4.87 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 17 | 17 | 8 | 4 | 4.23 | .314 | 1.33 | 9.1 | 2.9 | 5.3 | 110.2 | 111 | 54 | 52 | 7 | 36 | 65 | 2 | 0 | 0 | 1 | 9 | 5 | 8 | 3.76 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 17 | 17 | 3 | 10 | 5.03 | .326 | 1.42 | 10.3 | 2.5 | 4.0 | 107.1 | 122 | 64 | 60 | 16 | 30 | 47 | 5 | 0 | 0 | 1 | 7 | 4 | 2 | 5.02 |
| RP | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 42 | 0 | 4 | 0 | 2.61 | .268 | 1.10 | 6.8 | 3.0 | 10.2 | 62.0 | 47 | 18 | 18 | 2 | 21 | 70 | 0 | 6 | 1 | 0 | 0 | 0 | 1 | 2.18 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 45 | 0 | 2 | 2 | 3.81 | .266 | 1.07 | 7.0 | 2.6 | 8.2 | 59.0 | 46 | 25 | 25 | 6 | 17 | 54 | 0 | 7 | 2 | 0 | 0 | 1 | 3 | 3.41 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 32 | 0 | 2 | 1 | 2.47 | .260 | 1.03 | 5.7 | 3.8 | 7.1 | 43.2 | 27 | 12 | 12 | 4 | 18 | 34 | 0 | 5 | 0 | 0 | 0 | 1 | 0 | 3.95 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 13 | 0 | 3 | 0 | 0.96 | .192 | 0.71 | 4.5 | 1.9 | 8.0 | 28.0 | 14 | 3 | 3 | 2 | 6 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.79 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |