| SP | Martinez, P.Martinez, Pedro $ >> | 29 | 2000 | R | 100 | 12 | 12 | 4 | 5 | 3.67 | .305 | 1.28 | 8.9 | 2.6 | 8.8 | 76.0 | 75 | 39 | 31 | 8 | 22 | 74 | 2 | 0 | 0 | 0 | 6 | 3 | 0 | 3.41 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 12 | 12 | 4 | 3 | 4.42 | .304 | 1.30 | 9.0 | 2.7 | 7.5 | 73.1 | 73 | 41 | 36 | 11 | 22 | 61 | 1 | 0 | 0 | 1 | 5 | 1 | 1 | 4.23 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 12 | 12 | 4 | 5 | 5.79 | .331 | 1.47 | 10.0 | 3.3 | 4.2 | 65.1 | 72 | 46 | 42 | 13 | 24 | 30 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 5.83 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 12 | 12 | 2 | 7 | 5.79 | .316 | 1.37 | 9.2 | 3.3 | 3.2 | 60.2 | 61 | 40 | 39 | 8 | 22 | 21 | 1 | 0 | 0 | 0 | 5 | 1 | 0 | 5.18 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 31 | 0 | 2 | 2 | 4.33 | .284 | 1.13 | 7.2 | 3.1 | 11.1 | 35.1 | 28 | 17 | 17 | 5 | 12 | 43 | 0 | 8 | 4 | 0 | 0 | 2 | 1 | 3.60 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 32 | 0 | 1 | 1 | 3.63 | .328 | 1.44 | 9.9 | 3.2 | 9.0 | 39.2 | 43 | 20 | 16 | 4 | 14 | 39 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.49 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 36 | 0 | 2 | 0 | 1.59 | .265 | 1.08 | 5.2 | 4.6 | 8.0 | 45.1 | 26 | 8 | 8 | 0 | 23 | 40 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 2.76 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 33 | 0 | 3 | 2 | 2.23 | .234 | 0.89 | 6.5 | 1.6 | 9.7 | 40.1 | 29 | 10 | 10 | 2 | 7 | 43 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 2.10 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 78 | 32 | 0 | 4 | 2 | 6.64 | .318 | 1.40 | 8.3 | 4.4 | 8.5 | 39.1 | 36 | 31 | 29 | 8 | 19 | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 5.23 |