| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 33 | 33 | 12 | 18 | 4.25 | .300 | 1.27 | 8.8 | 2.6 | 4.8 | 262.1 | 256 | 128 | 124 | 35 | 76 | 141 | 11 | 0 | 0 | 0 | 16 | 6 | 3 | 4.60 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 32 | 32 | 9 | 13 | 4.83 | .318 | 1.39 | 9.2 | 3.4 | 8.0 | 212.1 | 216 | 125 | 114 | 29 | 80 | 189 | 2 | 0 | 0 | 2 | 18 | 1 | 5 | 4.14 |
| SP | Gooden, D.Gooden, Dwight # >> | 21 | 1985 | R | 68 | 32 | 32 | 7 | 21 | 5.23 | .329 | 1.46 | 10.0 | 3.2 | 7.5 | 235.2 | 260 | 150 | 137 | 36 | 83 | 196 | 9 | 0 | 0 | 0 | 10 | 4 | 7 | 4.43 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 30 | 30 | 9 | 18 | 6.83 | .377 | 1.81 | 12.0 | 4.3 | 4.1 | 196.1 | 262 | 151 | 149 | 30 | 93 | 90 | 7 | 0 | 0 | 1 | 9 | 1 | 8 | 5.51 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 84 | 0 | 5 | 6 | 4.23 | .297 | 1.25 | 6.6 | 4.7 | 8.2 | 123.1 | 90 | 60 | 58 | 13 | 64 | 112 | 0 | 12 | 0 | 0 | 0 | 2 | 0 | 4.16 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 65 | 61 | 0 | 3 | 4 | 3.38 | .253 | 0.99 | 6.1 | 2.9 | 8.3 | 74.2 | 50 | 28 | 28 | 9 | 24 | 68 | 0 | 8 | 2 | 0 | 0 | 2 | 3 | 3.80 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 36 | 0 | 1 | 4 | 6.42 | .384 | 1.87 | 11.2 | 6.0 | 7.9 | 33.2 | 41 | 26 | 24 | 5 | 22 | 29 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 5.21 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 49 | 38 | 0 | 1 | 2 | 5.36 | .316 | 1.34 | 8.4 | 3.6 | 5.6 | 47.0 | 44 | 29 | 28 | 11 | 19 | 29 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 6.15 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 2 | 0 | 0 | 0 | 20.25 | .579 | 4.13 | 36.0 | 13.5 | 4.5 | 2.2 | 8 | 6 | 6 | 1 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.00 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 22 | 0 | 3 | 0 | 8.92 | .350 | 1.61 | 10.5 | 4.1 | 6.2 | 35.1 | 41 | 35 | 35 | 7 | 16 | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.60 |