| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 28 | 28 | 9 | 10 | 4.02 | .312 | 1.36 | 8.5 | 3.7 | 8.1 | 177.0 | 167 | 82 | 79 | 13 | 73 | 159 | 1 | 0 | 0 | 0 | 16 | 1 | 0 | 3.41 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 28 | 28 | 11 | 8 | 4.63 | .320 | 1.39 | 8.7 | 3.9 | 5.8 | 194.1 | 188 | 102 | 100 | 28 | 83 | 124 | 3 | 0 | 0 | 1 | 12 | 3 | 6 | 4.93 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 26 | 26 | 9 | 11 | 5.09 | .321 | 1.39 | 9.6 | 2.9 | 8.3 | 168.0 | 179 | 101 | 95 | 29 | 54 | 155 | 2 | 0 | 0 | 0 | 11 | 5 | 5 | 4.45 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 67 | 27 | 27 | 13 | 8 | 3.82 | .284 | 1.18 | 7.8 | 2.8 | 6.1 | 188.2 | 163 | 85 | 80 | 20 | 59 | 127 | 6 | 0 | 0 | 2 | 15 | 3 | 1 | 4.02 |
| RP | Street, H.Street, Huston # >> | 29 | 2012 | R | 95 | 68 | 0 | 4 | 4 | 4.74 | .311 | 1.33 | 7.6 | 4.4 | 7.9 | 93.0 | 79 | 49 | 49 | 11 | 45 | 82 | 0 | 9 | 1 | 0 | 0 | 2 | 1 | 4.29 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 62 | 0 | 4 | 5 | 4.09 | .306 | 1.29 | 8.4 | 3.4 | 8.6 | 72.2 | 67 | 34 | 33 | 7 | 27 | 69 | 0 | 8 | 2 | 0 | 0 | 2 | 1 | 3.56 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 49 | 0 | 3 | 3 | 4.92 | .314 | 1.34 | 9.6 | 2.6 | 9.3 | 60.1 | 64 | 33 | 33 | 12 | 17 | 62 | 0 | 2 | 3 | 0 | 0 | 2 | 1 | 4.48 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 31 | 0 | 3 | 2 | 3.11 | .276 | 1.14 | 8.3 | 2.2 | 8.0 | 37.2 | 34 | 13 | 13 | 3 | 9 | 33 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 3.00 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 50 | 3 | 1 | 1 | 0 | 4.85 | .304 | 1.23 | 8.3 | 2.8 | 6.9 | 13.0 | 12 | 7 | 7 | 1 | 4 | 10 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 3.62 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 12 | 1 | 0 | 3 | 7.88 | .415 | 2.13 | 14.6 | 4.5 | 6.4 | 24.0 | 39 | 22 | 21 | 3 | 12 | 17 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 4.71 |