| SP | deGrom, J.deGrom, Jacob † $$ >> | 33 | 2021 | R | 100 | 29 | 29 | 15 | 8 | 3.75 | .269 | 1.09 | 7.7 | 2.1 | 9.2 | 187.1 | 160 | 84 | 78 | 19 | 44 | 191 | 3 | 0 | 0 | 1 | 17 | 3 | 0 | 3.03 |
| SP | Greinke, Z.Greinke, Zack # $ >> | 32 | 2015 | R | 94 | 28 | 28 | 16 | 7 | 3.89 | .284 | 1.19 | 8.3 | 2.4 | 5.9 | 208.0 | 191 | 94 | 90 | 19 | 56 | 137 | 3 | 0 | 0 | 1 | 16 | 1 | 6 | 3.69 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 26 | 26 | 10 | 10 | 4.82 | .321 | 1.39 | 9.7 | 2.8 | 4.4 | 177.1 | 191 | 102 | 95 | 21 | 55 | 87 | 4 | 0 | 0 | 0 | 13 | 5 | 5 | 4.58 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 72 | 0 | 5 | 3 | 3.70 | .323 | 1.42 | 7.8 | 5.0 | 7.8 | 97.1 | 84 | 42 | 40 | 9 | 54 | 84 | 0 | 11 | 2 | 0 | 0 | 1 | 0 | 4.18 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 51 | 0 | 7 | 3 | 2.30 | .251 | 1.01 | 5.2 | 4.0 | 10.8 | 66.2 | 38 | 18 | 17 | 2 | 29 | 79 | 0 | 8 | 1 | 0 | 0 | 0 | 0 | 2.32 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 34 | 0 | 2 | 2 | 2.27 | .308 | 1.34 | 9.7 | 2.5 | 6.5 | 39.2 | 42 | 13 | 10 | 4 | 11 | 28 | 0 | 7 | 1 | 0 | 0 | 0 | 0 | 3.74 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 17 | 0 | 0 | 0 | 3.93 | .313 | 1.36 | 9.0 | 3.5 | 5.0 | 18.1 | 18 | 8 | 8 | 1 | 7 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3.78 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 22 | 0 | 1 | 0 | 5.33 | .339 | 1.54 | 7.6 | 6.5 | 5.0 | 25.1 | 21 | 17 | 15 | 4 | 18 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.12 |