| SP | Kershaw, C.Kershaw, Clayton $ >> | 28 | 2016 | L | 99 | 21 | 21 | 9 | 5 | 3.47 | .291 | 1.22 | 8.7 | 2.3 | 6.6 | 145.1 | 140 | 59 | 56 | 20 | 37 | 107 | 2 | 0 | 0 | 0 | 14 | 2 | 4 | 4.12 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 81 | 20 | 20 | 9 | 3 | 3.37 | .268 | 1.07 | 6.4 | 3.2 | 6.8 | 125.2 | 89 | 48 | 47 | 14 | 45 | 94 | 0 | 0 | 0 | 0 | 14 | 4 | 6 | 4.13 |
| SP | Fernandez, S.Fernandez, Sid † >> | 23 | 1985 | L | 49 | 20 | 20 | 10 | 3 | 2.86 | .272 | 1.11 | 5.9 | 4.0 | 7.4 | 132.0 | 87 | 43 | 42 | 8 | 59 | 108 | 3 | 0 | 0 | 2 | 14 | 2 | 2 | 3.54 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 19 | 19 | 11 | 3 | 3.87 | .291 | 1.20 | 8.3 | 2.5 | 7.3 | 132.2 | 122 | 58 | 57 | 16 | 37 | 107 | 4 | 0 | 0 | 1 | 11 | 4 | 3 | 3.89 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 19 | 19 | 8 | 6 | 4.24 | .296 | 1.24 | 8.0 | 3.3 | 4.3 | 116.2 | 103 | 60 | 55 | 16 | 42 | 56 | 0 | 0 | 0 | 0 | 9 | 2 | 1 | 4.97 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 43 | 0 | 4 | 9 | 4.28 | .260 | 1.06 | 7.3 | 2.3 | 7.7 | 48.1 | 39 | 25 | 23 | 5 | 12 | 41 | 0 | 24 | 4 | 0 | 0 | 0 | 2 | 3.40 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 29 | 0 | 2 | 1 | 4.18 | .248 | 0.99 | 7.0 | 2.0 | 9.3 | 32.1 | 25 | 15 | 15 | 5 | 7 | 33 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.63 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 20 | 0 | 5 | 0 | 0.82 | .250 | 0.95 | 4.9 | 3.7 | 10.6 | 22.0 | 12 | 2 | 2 | 2 | 9 | 26 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.18 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 12 | 0 | 0 | 0 | 2.25 | .273 | 1.13 | 9.0 | 1.1 | 8.4 | 16.0 | 16 | 4 | 4 | 1 | 2 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.31 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 14 | 0 | 0 | 1 | 5.68 | .356 | 1.50 | 10.5 | 3.8 | 11.3 | 12.2 | 14 | 8 | 8 | 3 | 5 | 15 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 5.50 |