| SP | Walsh, E.Walsh, Ed # $$ >> | 29 | 1910 | R | 93 | 33 | 33 | 15 | 12 | 4.22 | .304 | 1.29 | 9.1 | 2.5 | 5.5 | 251.2 | 253 | 130 | 118 | 21 | 71 | 152 | 10 | 0 | 0 | 1 | 19 | 6 | 4 | 3.80 |
| SP | Tiant, L.Tiant, Luis $$ >> | 28 | 1968 | R | 97 | 34 | 34 | 13 | 15 | 4.05 | .311 | 1.33 | 8.4 | 3.6 | 8.3 | 251.0 | 233 | 117 | 113 | 18 | 100 | 232 | 2 | 0 | 0 | 0 | 17 | 7 | 3 | 3.36 |
| SP | Mathewson, C.Mathewson, Christy $ >> | 28 | 1908 | R | 83 | 32 | 32 | 14 | 12 | 4.26 | .297 | 1.24 | 8.5 | 2.7 | 5.7 | 230.1 | 217 | 124 | 109 | 29 | 68 | 146 | 4 | 0 | 0 | 1 | 16 | 7 | 5 | 4.35 |
| SP | Arrieta, J.Arrieta, Jake $ >> | 29 | 2015 | R | 92 | 32 | 32 | 8 | 18 | 4.89 | .340 | 1.54 | 10.3 | 3.6 | 8.6 | 228.1 | 262 | 144 | 124 | 28 | 90 | 219 | 6 | 0 | 0 | 0 | 16 | 1 | 4 | 3.87 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 78 | 31 | 31 | 5 | 18 | 5.89 | .359 | 1.65 | 11.0 | 3.9 | 5.4 | 214.0 | 261 | 156 | 140 | 27 | 93 | 129 | 5 | 0 | 0 | 0 | 13 | 5 | 4 | 4.81 |
| CL | Gagne, E.Gagne, Eric $ >> | 27 | 2003 | R | 98 | 54 | 0 | 1 | 7 | 3.34 | .313 | 1.37 | 7.6 | 4.7 | 10.5 | 59.1 | 50 | 22 | 22 | 0 | 31 | 69 | 0 | 31 | 6 | 0 | 0 | 0 | 0 | 2.24 |
| SU | Miller, A.Miller, Andrew # $$ >> | 29 | 2014 | L | 88 | 42 | 0 | 1 | 4 | 4.99 | .339 | 1.49 | 9.5 | 4.2 | 9.9 | 39.2 | 41 | 27 | 22 | 6 | 18 | 43 | 0 | 3 | 8 | 0 | 0 | 2 | 0 | 4.33 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 66 | 0 | 4 | 1 | 2.89 | .264 | 1.06 | 7.1 | 2.5 | 8.2 | 71.2 | 56 | 25 | 23 | 5 | 20 | 65 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 2.97 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 42 | 0 | 3 | 2 | 3.82 | .327 | 1.41 | 6.1 | 6.8 | 8.5 | 37.2 | 25 | 18 | 16 | 3 | 28 | 35 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 4.59 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 16 | 0 | 2 | 3 | 3.20 | .306 | 1.32 | 8.1 | 4.3 | 10.9 | 19.2 | 17 | 9 | 7 | 0 | 9 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 14 | 0 | 2 | 1 | 1.15 | .319 | 1.40 | 5.4 | 7.8 | 3.0 | 15.2 | 9 | 2 | 2 | 0 | 13 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.93 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 17 | 0 | 0 | 0 | 3.57 | .312 | 1.36 | 8.5 | 4.2 | 6.9 | 17.2 | 16 | 8 | 7 | 3 | 8 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 5.18 |