| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 21 | 21 | 11 | 5 | 3.44 | .293 | 1.22 | 8.4 | 2.6 | 8.5 | 157.0 | 146 | 60 | 60 | 16 | 46 | 148 | 4 | 0 | 0 | 0 | 11 | 3 | 3 | 3.38 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 19 | 19 | 8 | 6 | 5.70 | .333 | 1.46 | 10.3 | 2.9 | 5.1 | 126.1 | 144 | 81 | 80 | 20 | 41 | 71 | 5 | 0 | 0 | 0 | 7 | 4 | 1 | 5.01 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 20 | 19 | 7 | 8 | 4.90 | .305 | 1.30 | 8.9 | 2.8 | 6.3 | 128.2 | 127 | 73 | 70 | 15 | 40 | 90 | 4 | 0 | 0 | 0 | 10 | 2 | 2 | 4.10 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 27 | 0 | 1 | 2 | 4.09 | .331 | 1.45 | 8.7 | 4.4 | 7.9 | 33.0 | 32 | 15 | 15 | 2 | 16 | 29 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.58 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 24 | 0 | 5 | 2 | 3.29 | .299 | 1.28 | 7.7 | 4.0 | 6.3 | 27.1 | 23 | 10 | 10 | 2 | 12 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.89 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 20 | 0 | 1 | 0 | 0.36 | .191 | 0.71 | 2.9 | 3.6 | 9.0 | 25.1 | 8 | 1 | 1 | 0 | 10 | 25 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.20 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 13 | 0 | 1 | 0 | 3.52 | .403 | 2.02 | 11.4 | 7.2 | 9.6 | 15.1 | 19 | 7 | 6 | 2 | 12 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |