| SP | Verlander, J.Verlander, Justin $ >> | 36 | 2019 | R | 99 | 16 | 16 | 6 | 7 | 6.08 | .333 | 1.48 | 10.3 | 3.0 | 9.3 | 87.1 | 100 | 61 | 59 | 11 | 29 | 90 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 3.64 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 16 | 16 | 2 | 7 | 5.36 | .341 | 1.53 | 10.3 | 3.5 | 8.5 | 97.1 | 111 | 60 | 58 | 8 | 38 | 92 | 0 | 0 | 0 | 0 | 6 | 2 | 3 | 3.41 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 74 | 16 | 16 | 5 | 6 | 6.22 | .334 | 1.49 | 10.0 | 3.5 | 5.5 | 98.1 | 109 | 70 | 68 | 15 | 38 | 60 | 1 | 0 | 0 | 0 | 5 | 1 | 1 | 4.96 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 73 | 16 | 15 | 8 | 2 | 4.56 | .319 | 1.38 | 9.7 | 2.8 | 5.0 | 92.2 | 99 | 51 | 47 | 11 | 29 | 51 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 4.46 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 32 | 0 | 0 | 7 | 4.70 | .343 | 1.53 | 9.3 | 4.8 | 9.0 | 30.2 | 31 | 19 | 16 | 5 | 16 | 30 | 0 | 14 | 2 | 0 | 0 | 1 | 0 | 4.87 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 31 | 0 | 2 | 3 | 4.11 | .271 | 1.09 | 7.2 | 2.6 | 6.7 | 35.0 | 28 | 19 | 16 | 1 | 10 | 26 | 0 | 3 | 3 | 0 | 0 | 1 | 0 | 2.83 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 40 | 0 | 2 | 2 | 5.65 | .328 | 1.44 | 8.6 | 4.4 | 10.7 | 43.0 | 41 | 28 | 27 | 7 | 21 | 51 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 4.28 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 31 | 0 | 2 | 1 | 4.03 | .370 | 1.76 | 9.3 | 6.5 | 9.0 | 29.0 | 30 | 13 | 13 | 2 | 21 | 29 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.07 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 12 | 0 | 1 | 0 | 3.91 | .303 | 1.28 | 8.6 | 3.1 | 6.3 | 50.2 | 48 | 23 | 22 | 4 | 17 | 35 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 3.72 |