| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 21 | 21 | 9 | 6 | 3.47 | .281 | 1.16 | 7.4 | 3.0 | 10.9 | 137.1 | 113 | 61 | 53 | 22 | 46 | 166 | 0 | 0 | 0 | 0 | 13 | 2 | 0 | 3.72 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 85 | 20 | 20 | 3 | 11 | 6.30 | .348 | 1.57 | 11.3 | 3.0 | 8.4 | 115.2 | 144 | 90 | 81 | 27 | 38 | 107 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 5.26 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 20 | 20 | 4 | 7 | 6.15 | .361 | 1.68 | 11.5 | 3.7 | 5.2 | 101.0 | 129 | 78 | 69 | 13 | 41 | 58 | 0 | 0 | 0 | 0 | 4 | 1 | 3 | 4.77 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 18 | 18 | 5 | 11 | 7.31 | .383 | 1.85 | 11.5 | 5.2 | 7.1 | 108.1 | 138 | 97 | 88 | 21 | 62 | 85 | 2 | 0 | 0 | 0 | 4 | 2 | 5 | 5.73 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 58 | 0 | 2 | 1 | 7.06 | .346 | 1.57 | 9.4 | 4.8 | 10.8 | 51.0 | 53 | 40 | 40 | 8 | 27 | 61 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 4.29 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 52 | 0 | 2 | 1 | 2.72 | .254 | 1.02 | 5.8 | 3.4 | 8.7 | 53.0 | 34 | 16 | 16 | 4 | 20 | 51 | 0 | 6 | 2 | 0 | 0 | 0 | 2 | 3.19 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 1 | 1 | 0 | 1 | 13.50 | .471 | 2.67 | 19.5 | 4.5 | 3.0 | 6.0 | 13 | 9 | 9 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.83 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 12 | 1 | 1 | 3 | 5.87 | .395 | 1.96 | 13.2 | 4.8 | 6.6 | 15.1 | 22 | 12 | 10 | 3 | 8 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.73 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 42 | 0 | 4 | 1 | 4.05 | .308 | 1.30 | 9.5 | 2.3 | 7.5 | 60.0 | 63 | 30 | 27 | 5 | 15 | 50 | 0 | 4 | 0 | 0 | 0 | 2 | 2 | 3.27 |