| SP | Leonard, D.Leonard, Dutch $ >> | 22 | 1914 | L | 90 | 16 | 16 | 10 | 6 | 2.85 | .273 | 1.11 | 6.9 | 3.1 | 3.9 | 110.1 | 84 | 36 | 35 | 5 | 38 | 48 | 2 | 0 | 0 | 1 | 12 | 2 | 0 | 3.81 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 16 | 16 | 6 | 4 | 3.67 | .288 | 1.20 | 8.3 | 2.6 | 4.6 | 100.2 | 92 | 41 | 41 | 14 | 29 | 51 | 0 | 0 | 0 | 0 | 9 | 1 | 0 | 4.70 |
| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 65 | 13 | 13 | 8 | 4 | 3.71 | .283 | 1.16 | 8.4 | 2.1 | 7.8 | 106.2 | 99 | 45 | 44 | 10 | 25 | 92 | 3 | 0 | 0 | 0 | 7 | 2 | 0 | 3.25 |
| RP | Chapman, A.Chapman, Aroldis $ >> | 26 | 2014 | L | 94 | 38 | 0 | 2 | 3 | 3.38 | .273 | 1.13 | 5.1 | 5.1 | 8.6 | 42.2 | 24 | 16 | 16 | 2 | 24 | 40 | 0 | 7 | 2 | 0 | 0 | 0 | 1 | 3.43 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 15 | 0 | 0 | 2 | 3.32 | .296 | 1.21 | 9.0 | 1.9 | 6.6 | 19.0 | 19 | 7 | 7 | 0 | 4 | 14 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 2.32 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 15 | 0 | 2 | 1 | 2.51 | .157 | 0.56 | 3.2 | 1.9 | 7.1 | 14.1 | 5 | 4 | 4 | 1 | 3 | 11 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.00 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 8 | 0 | 3 | 1 | 3.60 | .310 | 1.35 | 6.3 | 5.9 | 11.3 | 20.0 | 14 | 8 | 8 | 3 | 13 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.40 |