| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 97 | 21 | 21 | 8 | 8 | 3.80 | .289 | 1.19 | 8.1 | 2.6 | 7.9 | 142.0 | 128 | 62 | 60 | 18 | 41 | 125 | 1 | 0 | 0 | 0 | 12 | 4 | 6 | 3.84 |
| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 90 | 20 | 20 | 13 | 4 | 2.62 | .281 | 1.13 | 6.0 | 4.2 | 8.2 | 141.0 | 94 | 46 | 41 | 8 | 66 | 129 | 1 | 0 | 0 | 1 | 15 | 5 | 2 | 3.42 |
| SP | Mathewson, C.Mathewson, Christy >> | 29 | 1909 | R | 86 | 20 | 20 | 11 | 4 | 3.65 | .282 | 1.15 | 8.0 | 2.4 | 3.9 | 128.1 | 114 | 53 | 52 | 10 | 34 | 56 | 2 | 0 | 0 | 1 | 13 | 3 | 2 | 4.01 |
| RP | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 46 | 0 | 2 | 2 | 1.94 | .252 | 0.98 | 5.1 | 3.8 | 9.6 | 60.1 | 34 | 14 | 13 | 4 | 25 | 64 | 0 | 11 | 1 | 0 | 0 | 2 | 1 | 3.08 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 29 | 0 | 3 | 1 | 4.61 | .305 | 1.24 | 9.0 | 2.3 | 7.3 | 27.1 | 27 | 14 | 14 | 2 | 7 | 22 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 3.33 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 16 | 0 | 0 | 2 | 3.63 | .288 | 1.15 | 9.0 | 1.6 | 6.9 | 17.1 | 17 | 7 | 7 | 3 | 3 | 13 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 4.47 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 6 | 0 | 2 | 1 | 1.84 | .267 | 1.09 | 6.4 | 3.9 | 6.4 | 14.2 | 10 | 4 | 3 | 1 | 6 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.79 |