| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 32 | 32 | 11 | 16 | 4.33 | .298 | 1.26 | 9.2 | 2.1 | 8.5 | 243.0 | 249 | 122 | 117 | 29 | 58 | 229 | 7 | 0 | 0 | 1 | 14 | 3 | 7 | 3.42 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 75 | 31 | 31 | 8 | 17 | 5.47 | .347 | 1.57 | 10.3 | 3.9 | 4.1 | 215.2 | 246 | 144 | 131 | 35 | 93 | 97 | 4 | 0 | 0 | 1 | 10 | 5 | 2 | 5.58 |
| SP | Chesbro, J.Chesbro, Jack † # >> | 30 | 1904 | R | 65 | 31 | 31 | 17 | 11 | 3.84 | .299 | 1.26 | 8.2 | 3.1 | 4.4 | 241.1 | 219 | 112 | 103 | 25 | 84 | 119 | 17 | 0 | 0 | 1 | 19 | 6 | 7 | 4.48 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 63 | 29 | 29 | 7 | 10 | 5.69 | .345 | 1.55 | 10.0 | 4.1 | 4.0 | 186.2 | 206 | 122 | 118 | 31 | 84 | 82 | 1 | 0 | 0 | 0 | 14 | 5 | 3 | 5.72 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 77 | 0 | 6 | 2 | 2.60 | .267 | 1.08 | 7.2 | 2.5 | 8.0 | 97.0 | 78 | 32 | 28 | 12 | 27 | 86 | 0 | 10 | 5 | 0 | 0 | 1 | 4 | 3.70 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 38 | 0 | 3 | 1 | 4.02 | .320 | 1.41 | 7.9 | 5.0 | 7.9 | 40.1 | 35 | 20 | 18 | 2 | 22 | 35 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.55 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 28 | 0 | 0 | 0 | 6.61 | .391 | 1.87 | 7.9 | 9.3 | 8.2 | 32.2 | 28 | 24 | 24 | 5 | 33 | 29 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 6.50 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 11 | 0 | 1 | 1 | 4.11 | .292 | 1.24 | 9.6 | 1.8 | 9.6 | 15.1 | 16 | 7 | 7 | 1 | 3 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 2.33 |