| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 97 | 33 | 33 | 12 | 16 | 4.99 | .325 | 1.41 | 9.9 | 2.9 | 9.8 | 196.2 | 215 | 111 | 109 | 26 | 63 | 214 | 0 | 0 | 0 | 0 | 15 | 6 | 6 | 3.60 |
| SP | Gilbert, L.Gilbert, Logan >> | 28 | 2025 | R | 91 | 33 | 33 | 5 | 13 | 6.95 | .369 | 1.69 | 11.5 | 3.8 | 10.0 | 146.1 | 186 | 115 | 113 | 26 | 62 | 162 | 0 | 0 | 0 | 0 | 8 | 9 | 7 | 4.55 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 82 | 34 | 33 | 3 | 13 | 4.73 | .338 | 1.49 | 9.4 | 4.1 | 8.2 | 150.1 | 156 | 83 | 79 | 13 | 68 | 137 | 0 | 0 | 0 | 0 | 7 | 6 | 1 | 3.78 |
| SP | Castillo, L.Castillo, Luis >> | 32 | 2025 | R | 67 | 35 | 31 | 14 | 13 | 5.27 | .343 | 1.56 | 10.6 | 3.5 | 7.8 | 160.2 | 189 | 96 | 94 | 24 | 62 | 138 | 0 | 0 | 0 | 0 | 12 | 1 | 4 | 4.41 |
| CL | Chapman, A.Chapman, Aroldis † >> | 37 | 2025 | L | 100 | 87 | 0 | 9 | 4 | 2.50 | .303 | 1.26 | 6.4 | 4.9 | 10.3 | 101.0 | 72 | 28 | 28 | 6 | 55 | 116 | 0 | 29 | 0 | 0 | 0 | 5 | 8 | 3.26 |
| SU | Munoz, A.Munoz, Andres >> | 26 | 2025 | R | 90 | 96 | 0 | 1 | 3 | 3.17 | .303 | 1.28 | 6.3 | 5.3 | 8.5 | 113.2 | 79 | 41 | 40 | 5 | 67 | 107 | 0 | 3 | 3 | 0 | 0 | 2 | 12 | 3.51 |
| RP | Kittredge, A.Kittredge, Andrew † >> | 35 | 2025 | R | 84 | 104 | 0 | 16 | 1 | 4.10 | .322 | 1.40 | 9.5 | 3.1 | 10.5 | 116.1 | 123 | 59 | 53 | 9 | 40 | 135 | 0 | 2 | 2 | 0 | 0 | 3 | 2 | 2.79 |
| RP | Saalfrank, A.Saalfrank, Andrew >> | 27 | 2025 | L | 81 | 112 | 0 | 6 | 3 | 3.38 | .275 | 1.10 | 7.3 | 2.7 | 7.6 | 119.2 | 96 | 46 | 45 | 11 | 36 | 100 | 0 | 7 | 3 | 0 | 0 | 4 | 5 | 3.53 |
| RP | Sterner, J.Sterner, Justin >> | 28 | 2025 | R | 77 | 101 | 0 | 3 | 1 | 3.33 | .299 | 1.27 | 6.7 | 4.8 | 9.9 | 100.0 | 74 | 37 | 37 | 12 | 53 | 110 | 0 | 1 | 3 | 0 | 0 | 1 | 1 | 3.98 |
| RP | Pomeranz, D.Pomeranz, Drew >> | 36 | 2025 | L | 71 | 94 | 0 | 5 | 4 | 2.54 | .277 | 1.13 | 7.5 | 2.7 | 10.6 | 106.1 | 88 | 32 | 30 | 8 | 32 | 125 | 0 | 2 | 6 | 0 | 0 | 2 | 2 | 2.58 |