| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 8 | 8 | 1 | 4 | 6.80 | .332 | 1.49 | 10.1 | 3.3 | 11.0 | 41.0 | 46 | 34 | 31 | 5 | 15 | 50 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 3.24 |
| SP | Crochet, G.Crochet, Garrett >> | 26 | 2025 | L | 89 | 7 | 7 | 1 | 3 | 6.14 | .368 | 1.75 | 12.8 | 3.3 | 9.0 | 36.2 | 51 | 25 | 25 | 7 | 13 | 36 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 4.61 |
| SP | Horton, C.Horton, Cade >> | 23 | 2025 | R | 79 | 7 | 7 | 3 | 2 | 4.17 | .321 | 1.39 | 9.3 | 3.5 | 6.5 | 36.2 | 37 | 17 | 17 | 4 | 14 | 26 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 4.25 |
| SP | Kelly, M.Kelly, Merrill >> | 36 | 2025 | R | 73 | 7 | 7 | 4 | 3 | 5.67 | .331 | 1.49 | 11.3 | 2.3 | 6.7 | 39.2 | 49 | 25 | 25 | 7 | 10 | 29 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 4.62 |
| RP | Morejon, A.Morejon, Adrian >> | 26 | 2025 | L | 88 | 18 | 0 | 1 | 0 | 4.35 | .319 | 1.40 | 7.7 | 5.4 | 7.7 | 20.2 | 17 | 10 | 10 | 3 | 12 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.05 |
| RP | Strahm, M.Strahm, Matt >> | 33 | 2025 | L | 72 | 15 | 0 | 2 | 0 | 2.75 | .280 | 1.12 | 8.5 | 1.9 | 10.9 | 19.2 | 18 | 6 | 6 | 3 | 4 | 23 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.42 |
| RP | Weaver, L.Weaver, Luke >> | 31 | 2025 | R | 83 | 10 | 0 | 0 | 1 | 5.40 | .322 | 1.43 | 10.4 | 2.8 | 9.7 | 13.1 | 15 | 8 | 8 | 4 | 4 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.77 |
| SP | Taillon, J.Taillon, Jameson >> | 33 | 2025 | R | 77 | 6 | 0 | 0 | 1 | 10.03 | .444 | 2.36 | 15.7 | 5.9 | 9.4 | 23.1 | 40 | 28 | 26 | 7 | 15 | 24 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 6.96 |