| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 8 | 8 | 3 | 3 | 4.57 | .304 | 1.30 | 9.0 | 2.7 | 7.5 | 61.0 | 61 | 33 | 31 | 7 | 18 | 51 | 1 | 0 | 0 | 1 | 4 | 1 | 2 | 3.75 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 75 | 8 | 8 | 3 | 2 | 5.15 | .337 | 1.47 | 9.8 | 3.8 | 8.3 | 36.2 | 39 | 21 | 21 | 6 | 15 | 33 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 4.75 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 72 | 8 | 8 | 2 | 2 | 6.42 | .364 | 1.72 | 12.2 | 3.5 | 6.2 | 54.2 | 73 | 40 | 39 | 9 | 21 | 37 | 1 | 0 | 0 | 0 | 1 | 0 | 4 | 4.96 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 65 | 8 | 8 | 4 | 3 | 3.54 | .317 | 1.36 | 9.0 | 3.2 | 4.4 | 61.0 | 61 | 25 | 24 | 4 | 22 | 30 | 0 | 0 | 0 | 0 | 4 | 2 | 2 | 4.05 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 63 | 8 | 8 | 2 | 4 | 7.63 | .351 | 1.58 | 12.1 | 2.3 | 6.9 | 43.2 | 58 | 42 | 37 | 13 | 11 | 33 | 1 | 0 | 0 | 1 | 2 | 2 | 2 | 6.30 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 22 | 0 | 2 | 0 | 2.70 | .256 | 1.03 | 7.2 | 2.1 | 10.5 | 30.0 | 24 | 9 | 9 | 2 | 7 | 35 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.23 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 80 | 18 | 0 | 0 | 3 | 4.64 | .354 | 1.64 | 9.9 | 5.1 | 11.6 | 21.1 | 23 | 11 | 11 | 3 | 12 | 27 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 4.00 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 18 | 0 | 2 | 0 | 3.28 | .204 | 0.77 | 4.9 | 2.3 | 8.3 | 24.2 | 13 | 9 | 9 | 0 | 6 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.92 |
| SP | DeLeon, J.DeLeon, Jose >> | 29 | 1989 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 54 | 2 | 0 | 0 | 1 | 10.80 | .565 | 3.90 | 27.0 | 12.0 | 6.0 | 3.1 | 9 | 4 | 4 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.67 |