| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 95 | 34 | 34 | 16 | 13 | 5.36 | .321 | 1.39 | 9.0 | 3.5 | 8.6 | 203.1 | 203 | 126 | 121 | 32 | 80 | 193 | 3 | 0 | 0 | 1 | 13 | 5 | 5 | 4.40 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 33 | 33 | 10 | 11 | 5.00 | .329 | 1.42 | 10.0 | 2.8 | 9.4 | 201.2 | 223 | 114 | 112 | 37 | 63 | 210 | 0 | 0 | 0 | 0 | 17 | 10 | 5 | 4.39 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 78 | 32 | 32 | 8 | 13 | 6.09 | .345 | 1.56 | 10.9 | 3.2 | 7.4 | 190.2 | 230 | 137 | 129 | 38 | 67 | 156 | 0 | 0 | 0 | 0 | 12 | 4 | 1 | 5.08 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 33 | 32 | 11 | 17 | 6.60 | .361 | 1.67 | 11.3 | 3.7 | 6.6 | 170.1 | 214 | 127 | 125 | 39 | 70 | 125 | 0 | 0 | 0 | 0 | 13 | 5 | 6 | 5.84 |
| SP | Gallen, Z.Gallen, Zac # $$ >> | 26 | 2022 | R | 92 | 31 | 31 | 15 | 6 | 3.80 | .290 | 1.20 | 7.7 | 3.1 | 9.4 | 187.0 | 160 | 84 | 79 | 26 | 64 | 196 | 1 | 0 | 0 | 1 | 15 | 5 | 2 | 3.82 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 81 | 83 | 0 | 3 | 3 | 4.74 | .292 | 1.21 | 7.0 | 3.9 | 9.4 | 76.0 | 59 | 40 | 40 | 15 | 33 | 79 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 4.87 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 76 | 62 | 0 | 5 | 4 | 3.78 | .320 | 1.35 | 7.5 | 4.8 | 11.0 | 64.1 | 53 | 29 | 27 | 10 | 34 | 78 | 0 | 0 | 4 | 0 | 0 | 4 | 0 | 4.38 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 68 | 51 | 0 | 2 | 2 | 4.07 | .311 | 1.36 | 7.5 | 4.9 | 8.3 | 48.2 | 40 | 23 | 22 | 6 | 26 | 44 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 4.42 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 66 | 31 | 0 | 1 | 0 | 4.94 | .396 | 1.87 | 8.4 | 8.4 | 11.0 | 31.0 | 29 | 17 | 17 | 2 | 29 | 38 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 4.48 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 58 | 74 | 0 | 0 | 4 | 6.09 | .342 | 1.51 | 10.1 | 3.6 | 9.3 | 57.2 | 64 | 39 | 39 | 13 | 23 | 59 | 0 | 1 | 1 | 0 | 0 | 3 | 2 | 5.26 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 62 | 29 | 0 | 2 | 1 | 9.07 | .384 | 1.85 | 13.3 | 3.4 | 8.3 | 84.1 | 124 | 85 | 85 | 26 | 32 | 77 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 6.40 |
| CL | Adams, M.Adams, Mike † $ >> | 31 | 2009 | R | 99 | 65 | 0 | 3 | 9 | 3.98 | .280 | 1.15 | 5.6 | 4.9 | 10.4 | 63.1 | 39 | 28 | 28 | 9 | 34 | 73 | 0 | 42 | 6 | 0 | 0 | 1 | 0 | 4.21 |