| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 15 | 15 | 12 | 3 | 2.55 | .230 | 0.88 | 5.9 | 2.0 | 4.4 | 106.0 | 70 | 30 | 30 | 8 | 23 | 52 | 2 | 0 | 0 | 1 | 12 | 2 | 0 | 3.71 |
| SP | Snell, B.Snell, Blake $ >> | 25 | 2018 | L | 81 | 14 | 14 | 3 | 6 | 3.51 | .246 | 0.97 | 5.8 | 3.0 | 8.5 | 89.2 | 57 | 35 | 35 | 9 | 30 | 84 | 1 | 0 | 0 | 1 | 9 | 1 | 1 | 3.47 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 15 | 15 | 8 | 3 | 3.48 | .288 | 1.18 | 7.9 | 2.7 | 7.3 | 93.0 | 82 | 38 | 36 | 5 | 28 | 75 | 0 | 0 | 0 | 0 | 9 | 3 | 1 | 3.09 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 14 | 14 | 5 | 8 | 3.77 | .276 | 1.13 | 7.7 | 2.5 | 5.5 | 117.0 | 100 | 58 | 49 | 8 | 32 | 72 | 7 | 0 | 0 | 0 | 6 | 2 | 4 | 3.53 |
| RP | Chapman, A.Chapman, Aroldis $ >> | 26 | 2014 | L | 94 | 35 | 0 | 1 | 3 | 2.74 | .250 | 0.98 | 4.5 | 4.3 | 9.2 | 46.0 | 23 | 14 | 14 | 2 | 22 | 47 | 0 | 4 | 3 | 0 | 0 | 1 | 1 | 3.02 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 19 | 0 | 0 | 2 | 4.29 | .292 | 1.24 | 8.1 | 3.0 | 7.7 | 21.0 | 19 | 10 | 10 | 2 | 7 | 18 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 3.52 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 15 | 0 | 2 | 0 | 0.46 | .263 | 0.92 | 3.8 | 4.7 | 6.2 | 19.2 | 8 | 1 | 1 | 0 | 10 | 13 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 3.68 |