| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 95 | 30 | 30 | 11 | 15 | 3.96 | .290 | 1.21 | 7.8 | 3.1 | 7.4 | 209.0 | 181 | 95 | 92 | 19 | 72 | 172 | 8 | 0 | 0 | 2 | 15 | 3 | 4 | 3.61 |
| SP | Maddux, G.Maddux, Greg $$ >> | 29 | 1995 | R | 89 | 29 | 29 | 15 | 8 | 3.76 | .278 | 1.14 | 8.5 | 1.7 | 5.1 | 217.2 | 206 | 95 | 91 | 23 | 42 | 123 | 12 | 0 | 0 | 3 | 17 | 3 | 2 | 3.87 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 25 | 25 | 13 | 6 | 3.77 | .306 | 1.30 | 6.4 | 5.3 | 6.8 | 169.2 | 120 | 72 | 71 | 12 | 100 | 128 | 0 | 0 | 0 | 0 | 17 | 4 | 2 | 4.25 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 72 | 0 | 7 | 1 | 2.64 | .276 | 1.12 | 6.3 | 3.8 | 7.9 | 99.0 | 69 | 29 | 29 | 7 | 42 | 87 | 0 | 15 | 2 | 0 | 0 | 2 | 0 | 3.49 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 44 | 0 | 8 | 2 | 3.58 | .260 | 1.01 | 6.5 | 2.7 | 9.0 | 50.1 | 36 | 21 | 20 | 6 | 15 | 50 | 0 | 3 | 2 | 0 | 0 | 2 | 0 | 3.58 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 25 | 0 | 4 | 3 | 2.39 | .218 | 0.84 | 3.8 | 3.8 | 4.8 | 26.1 | 11 | 7 | 7 | 1 | 11 | 14 | 0 | 7 | 0 | 0 | 0 | 0 | 2 | 3.69 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 65 | 12 | 0 | 0 | 2 | 6.10 | .340 | 1.55 | 12.6 | 1.8 | 6.3 | 10.1 | 14 | 7 | 7 | 5 | 2 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 8.70 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 8 | 0 | 1 | 1 | 6.14 | .353 | 1.64 | 10.3 | 5.1 | 11.6 | 7.1 | 8 | 5 | 5 | 3 | 4 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.71 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 17 | 0 | 1 | 0 | 1.64 | .233 | 0.91 | 4.9 | 3.3 | 6.5 | 33.0 | 18 | 6 | 6 | 0 | 12 | 24 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2.64 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 67 | 12 | 0 | 1 | 1 | 4.14 | .292 | 1.22 | 7.4 | 3.6 | 3.4 | 50.0 | 41 | 23 | 23 | 5 | 20 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.80 |