| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 30 | 30 | 8 | 12 | 4.25 | .299 | 1.25 | 8.1 | 3.2 | 8.5 | 207.2 | 186 | 104 | 98 | 33 | 73 | 195 | 3 | 0 | 0 | 1 | 16 | 7 | 2 | 4.35 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 79 | 29 | 29 | 9 | 12 | 4.40 | .303 | 1.29 | 8.8 | 2.9 | 8.4 | 202.1 | 197 | 107 | 99 | 29 | 65 | 188 | 3 | 0 | 0 | 1 | 16 | 2 | 8 | 4.00 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 28 | 28 | 11 | 12 | 4.55 | .322 | 1.40 | 9.5 | 3.1 | 7.9 | 193.2 | 204 | 109 | 98 | 27 | 67 | 170 | 4 | 0 | 0 | 2 | 15 | 5 | 5 | 4.18 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 73 | 0 | 4 | 3 | 2.93 | .264 | 1.03 | 6.2 | 3.0 | 9.5 | 104.1 | 72 | 42 | 34 | 8 | 35 | 110 | 0 | 4 | 3 | 0 | 0 | 5 | 0 | 3.04 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 68 | 0 | 7 | 2 | 2.87 | .269 | 1.11 | 6.1 | 3.8 | 7.3 | 94.0 | 64 | 31 | 30 | 4 | 40 | 76 | 0 | 4 | 3 | 0 | 0 | 0 | 1 | 3.21 |
| RP | Lidge, B.Lidge, Brad # >> | 28 | 2004 | R | 63 | 58 | 0 | 7 | 5 | 4.95 | .355 | 1.63 | 10.8 | 3.9 | 7.8 | 60.0 | 72 | 33 | 33 | 10 | 26 | 52 | 0 | 3 | 4 | 0 | 0 | 1 | 3 | 4.78 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 4 | 0 | 1 | 0 | 1.59 | .414 | 2.12 | 14.4 | 7.2 | 1.8 | 5.2 | 8 | 2 | 1 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 63 | 29 | 0 | 1 | 7 | 7.62 | .415 | 2.10 | 13.2 | 5.8 | 3.2 | 39.0 | 57 | 39 | 33 | 7 | 25 | 14 | 0 | 2 | 5 | 0 | 0 | 1 | 1 | 6.62 |