| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 32 | 32 | 6 | 15 | 4.98 | .317 | 1.36 | 9.5 | 2.8 | 8.8 | 209.2 | 220 | 125 | 116 | 27 | 65 | 205 | 2 | 0 | 0 | 1 | 13 | 7 | 3 | 3.75 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 33 | 33 | 12 | 13 | 5.33 | .339 | 1.51 | 10.0 | 3.6 | 8.4 | 192.2 | 214 | 126 | 114 | 32 | 77 | 180 | 1 | 0 | 0 | 1 | 15 | 6 | 3 | 4.59 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 32 | 32 | 3 | 17 | 6.77 | .379 | 1.79 | 11.8 | 4.3 | 5.8 | 198.0 | 260 | 163 | 149 | 30 | 94 | 127 | 1 | 0 | 0 | 0 | 10 | 9 | 4 | 5.25 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 31 | 31 | 13 | 13 | 5.04 | .327 | 1.45 | 9.8 | 3.3 | 7.0 | 210.2 | 229 | 122 | 118 | 30 | 76 | 164 | 1 | 0 | 0 | 1 | 15 | 2 | 3 | 4.41 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 83 | 0 | 6 | 6 | 5.32 | .324 | 1.39 | 8.7 | 3.8 | 8.3 | 130.1 | 126 | 81 | 77 | 21 | 55 | 120 | 0 | 12 | 7 | 0 | 0 | 6 | 0 | 4.66 |
| RP | Clippard, T.Clippard, Tyler † >> | 26 | 2011 | R | 79 | 83 | 0 | 12 | 5 | 4.06 | .329 | 1.44 | 8.0 | 4.9 | 8.0 | 102.0 | 91 | 50 | 46 | 7 | 56 | 91 | 0 | 11 | 4 | 0 | 0 | 3 | 2 | 3.84 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 75 | 0 | 3 | 4 | 3.76 | .287 | 1.20 | 8.5 | 2.4 | 7.7 | 83.2 | 78 | 37 | 35 | 11 | 22 | 71 | 0 | 15 | 4 | 0 | 0 | 1 | 2 | 3.84 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 47 | 0 | 2 | 3 | 5.43 | .374 | 1.77 | 11.7 | 4.2 | 7.3 | 53.0 | 69 | 35 | 32 | 9 | 25 | 43 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.06 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 67 | 3 | 0 | 0 | 0 | 0.00 | .200 | 0.75 | 9.0 | 0.0 | 0.0 | 2.2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 24 | 0 | 2 | 2 | 6.35 | .343 | 1.57 | 11.0 | 3.2 | 8.4 | 45.1 | 55 | 32 | 32 | 7 | 16 | 42 | 0 | 1 | 2 | 0 | 0 | 0 | 4 | 4.22 |