| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 12 | 12 | 4 | 4 | 3.66 | .285 | 1.15 | 6.8 | 3.6 | 9.5 | 86.0 | 65 | 36 | 35 | 7 | 34 | 91 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 3.27 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 11 | 11 | 4 | 6 | 3.78 | .310 | 1.30 | 8.3 | 3.3 | 6.0 | 81.0 | 75 | 38 | 34 | 9 | 30 | 54 | 5 | 0 | 0 | 1 | 6 | 4 | 2 | 4.37 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 63 | 11 | 10 | 1 | 7 | 5.21 | .334 | 1.45 | 10.0 | 3.2 | 4.8 | 65.2 | 72 | 39 | 38 | 10 | 23 | 35 | 2 | 0 | 0 | 0 | 4 | 4 | 1 | 5.17 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 10 | 10 | 3 | 3 | 4.43 | .334 | 1.51 | 8.9 | 4.7 | 4.3 | 65.0 | 64 | 34 | 32 | 6 | 34 | 31 | 1 | 0 | 0 | 0 | 5 | 0 | 2 | 4.82 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 10 | 9 | 4 | 3 | 4.34 | .320 | 1.37 | 8.4 | 3.9 | 4.8 | 64.1 | 60 | 36 | 31 | 4 | 28 | 34 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 4.20 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 25 | 0 | 1 | 1 | 4.76 | .351 | 1.62 | 7.7 | 7.1 | 7.7 | 28.1 | 24 | 15 | 15 | 4 | 22 | 24 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 5.50 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 22 | 0 | 2 | 1 | 3.38 | .368 | 1.69 | 8.4 | 6.8 | 7.3 | 32.0 | 30 | 12 | 12 | 1 | 24 | 26 | 0 | 6 | 1 | 0 | 0 | 2 | 0 | 4.22 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 4 | 3 | 1 | 1 | 6.87 | .402 | 2.02 | 14.0 | 4.5 | 6.5 | 18.1 | 28 | 17 | 14 | 1 | 9 | 13 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 3.78 |