| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 34 | 34 | 10 | 12 | 4.37 | .318 | 1.38 | 8.3 | 4.1 | 9.4 | 224.2 | 206 | 115 | 109 | 27 | 103 | 234 | 0 | 0 | 0 | 0 | 17 | 5 | 8 | 3.92 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 33 | 33 | 12 | 14 | 3.64 | .308 | 1.31 | 8.7 | 3.0 | 5.7 | 252.0 | 244 | 114 | 102 | 30 | 85 | 160 | 8 | 0 | 0 | 2 | 19 | 8 | 6 | 4.38 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 63 | 32 | 31 | 5 | 19 | 4.64 | .309 | 1.32 | 9.3 | 2.6 | 5.0 | 221.0 | 228 | 118 | 114 | 29 | 63 | 122 | 9 | 0 | 0 | 1 | 15 | 6 | 3 | 4.54 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 31 | 31 | 9 | 15 | 4.84 | .335 | 1.50 | 8.4 | 5.1 | 4.7 | 201.0 | 188 | 115 | 108 | 20 | 113 | 104 | 3 | 0 | 0 | 0 | 13 | 3 | 3 | 4.99 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 30 | 29 | 9 | 13 | 5.53 | .327 | 1.43 | 8.8 | 4.1 | 5.0 | 190.1 | 186 | 122 | 117 | 21 | 87 | 106 | 1 | 0 | 0 | 0 | 14 | 5 | 7 | 4.77 |
| RP | Feliz, N.Feliz, Neftali # >> | 21 | 2009 | R | 97 | 84 | 0 | 4 | 7 | 4.47 | .314 | 1.35 | 6.8 | 5.5 | 9.6 | 92.2 | 69 | 48 | 46 | 16 | 56 | 98 | 0 | 10 | 6 | 0 | 0 | 2 | 0 | 5.02 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 53 | 0 | 3 | 7 | 5.17 | .361 | 1.67 | 8.9 | 6.3 | 7.0 | 76.2 | 75 | 46 | 44 | 8 | 53 | 59 | 0 | 12 | 5 | 0 | 0 | 2 | 1 | 4.99 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 15 | 3 | 2 | 1 | 6.25 | .366 | 1.69 | 10.8 | 4.5 | 4.7 | 40.1 | 48 | 31 | 28 | 3 | 20 | 21 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 4.58 |