| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 36 | 36 | 14 | 12 | 3.68 | .290 | 1.20 | 9.0 | 1.8 | 7.3 | 256.2 | 257 | 125 | 105 | 29 | 52 | 207 | 4 | 0 | 0 | 1 | 22 | 6 | 5 | 3.54 |
| SP | Leonard, D.Leonard, Dutch † >> | 22 | 1914 | L | 91 | 34 | 34 | 14 | 8 | 3.81 | .281 | 1.16 | 7.2 | 3.3 | 5.0 | 215.0 | 171 | 94 | 91 | 21 | 79 | 119 | 0 | 0 | 0 | 0 | 21 | 2 | 3 | 4.29 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 33 | 33 | 11 | 10 | 3.54 | .296 | 1.24 | 7.0 | 4.2 | 4.6 | 223.2 | 174 | 97 | 88 | 15 | 103 | 113 | 3 | 0 | 0 | 1 | 18 | 5 | 3 | 4.31 |
| RP | Benitez, A.Benitez, Armando # >> | 32 | 2004 | R | 82 | 101 | 0 | 12 | 7 | 3.70 | .300 | 1.29 | 7.4 | 4.3 | 5.7 | 116.2 | 95 | 51 | 48 | 17 | 55 | 74 | 0 | 4 | 5 | 0 | 0 | 0 | 0 | 5.05 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 63 | 0 | 3 | 3 | 4.26 | .299 | 1.26 | 6.1 | 5.3 | 9.3 | 69.2 | 47 | 37 | 33 | 6 | 41 | 71 | 0 | 3 | 5 | 0 | 0 | 1 | 1 | 3.90 |
| RP | Holland, G.Holland, Greg # >> | 27 | 2013 | R | 72 | 47 | 0 | 1 | 3 | 5.44 | .348 | 1.58 | 9.2 | 5.1 | 9.9 | 48.0 | 49 | 32 | 29 | 12 | 27 | 53 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 5.79 |
| CL | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 76 | 0 | 4 | 7 | 3.59 | .317 | 1.37 | 7.1 | 5.3 | 8.4 | 80.1 | 63 | 33 | 32 | 7 | 47 | 75 | 0 | 36 | 5 | 0 | 0 | 2 | 2 | 4.10 |