| SP | Darvish, Y.Darvish, Yu † >> | 35 | 2022 | R | 98 | 19 | 19 | 8 | 5 | 3.20 | .270 | 1.10 | 7.9 | 2.0 | 9.6 | 132.1 | 116 | 51 | 47 | 19 | 30 | 141 | 1 | 0 | 0 | 1 | 14 | 1 | 4 | 3.44 |
| SP | Scherzer, M.Scherzer, Max >> | 39 | 2023 | R | 85 | 18 | 18 | 3 | 6 | 8.68 | .396 | 1.94 | 12.5 | 5.0 | 9.5 | 85.0 | 118 | 83 | 82 | 25 | 47 | 90 | 1 | 0 | 0 | 1 | 4 | 2 | 0 | 6.44 |
| SP | Eovaldi, N.Eovaldi, Nathan # >> | 33 | 2023 | R | 78 | 17 | 17 | 7 | 4 | 3.75 | .293 | 1.19 | 7.9 | 2.8 | 9.3 | 108.0 | 95 | 48 | 45 | 16 | 33 | 111 | 0 | 0 | 0 | 0 | 11 | 6 | 0 | 3.95 |
| SP | Assad, J.Assad, Javier >> | 25 | 2023 | R | 59 | 17 | 17 | 0 | 3 | 4.65 | .321 | 1.39 | 8.7 | 3.8 | 7.7 | 62.0 | 60 | 32 | 32 | 9 | 26 | 53 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.53 |
| RP | Hoffman, J.Hoffman, Jeff >> | 30 | 2023 | R | 98 | 46 | 0 | 3 | 3 | 4.31 | .306 | 1.31 | 7.8 | 4.1 | 11.5 | 62.2 | 54 | 30 | 30 | 9 | 28 | 79 | 0 | 2 | 4 | 0 | 0 | 1 | 4 | 3.74 |
| RP | Stewart, B.Stewart, Brock >> | 31 | 2023 | R | 84 | 44 | 0 | 5 | 5 | 6.35 | .339 | 1.50 | 9.5 | 4.2 | 10.1 | 56.2 | 59 | 40 | 40 | 10 | 26 | 63 | 0 | 3 | 3 | 0 | 0 | 2 | 2 | 4.57 |
| RP | Pressly, R.Pressly, Ryan >> | 34 | 2023 | R | 68 | 45 | 0 | 2 | 2 | 3.42 | .288 | 1.16 | 7.0 | 3.4 | 9.8 | 55.1 | 43 | 21 | 21 | 4 | 21 | 60 | 0 | 4 | 2 | 0 | 0 | 3 | 1 | 3.07 |
| RP | Brebbia, J.Brebbia, John >> | 33 | 2023 | R | 56 | 38 | 0 | 1 | 6 | 5.44 | .322 | 1.32 | 8.6 | 3.3 | 12.7 | 46.1 | 44 | 28 | 28 | 11 | 17 | 65 | 0 | 2 | 4 | 0 | 0 | 5 | 0 | 4.72 |
| RP | Robertson, D.Robertson, David >> | 38 | 2023 | R | 48 | 35 | 0 | 3 | 0 | 4.23 | .323 | 1.39 | 9.0 | 3.7 | 9.8 | 44.2 | 44 | 21 | 21 | 12 | 18 | 48 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 5.73 |
| SP | Javier, C.Javier, Cristian >> | 26 | 2023 | R | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Giolito, L.Giolito, Lucas >> | 28 | 2023 | R | 51 | 27 | 0 | 6 | 5 | 4.53 | .355 | 1.56 | 10.5 | 3.8 | 9.4 | 43.2 | 50 | 22 | 22 | 8 | 18 | 45 | 0 | 6 | 2 | 0 | 0 | 4 | 1 | 4.86 |