| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 22 | 22 | 10 | 8 | 4.26 | .304 | 1.29 | 8.8 | 2.8 | 8.8 | 129.0 | 126 | 62 | 61 | 9 | 40 | 126 | 1 | 0 | 0 | 0 | 13 | 3 | 0 | 2.95 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 21 | 21 | 5 | 8 | 6.17 | .341 | 1.55 | 10.6 | 3.5 | 6.3 | 109.1 | 128 | 75 | 75 | 19 | 42 | 76 | 1 | 0 | 0 | 1 | 7 | 0 | 7 | 5.03 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 21 | 21 | 7 | 5 | 4.54 | .310 | 1.33 | 9.0 | 3.0 | 7.8 | 117.0 | 117 | 62 | 59 | 21 | 39 | 101 | 1 | 0 | 0 | 0 | 10 | 2 | 1 | 4.66 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 43 | 0 | 1 | 6 | 3.43 | .291 | 1.21 | 7.8 | 3.3 | 9.4 | 44.2 | 38 | 17 | 17 | 6 | 16 | 46 | 0 | 20 | 2 | 0 | 0 | 1 | 2 | 3.84 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 53 | 0 | 1 | 1 | 3.86 | .265 | 1.03 | 6.6 | 2.7 | 8.3 | 63.0 | 46 | 29 | 27 | 7 | 19 | 58 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 3.65 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 76 | 26 | 0 | 4 | 0 | 2.23 | .292 | 1.24 | 9.0 | 2.3 | 10.7 | 32.1 | 32 | 8 | 8 | 2 | 8 | 38 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.19 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 29 | 0 | 0 | 0 | 4.28 | .331 | 1.49 | 8.2 | 5.5 | 5.2 | 33.2 | 30 | 18 | 16 | 4 | 20 | 19 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.24 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 24 | 0 | 8 | 1 | 2.80 | .260 | 1.03 | 7.5 | 1.9 | 5.5 | 99.2 | 82 | 38 | 31 | 9 | 21 | 61 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.65 |