| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 34 | 34 | 16 | 15 | 3.47 | .268 | 1.09 | 8.0 | 1.8 | 8.6 | 261.2 | 232 | 103 | 101 | 25 | 53 | 250 | 10 | 0 | 0 | 3 | 20 | 3 | 7 | 2.97 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 33 | 33 | 8 | 11 | 4.57 | .321 | 1.41 | 9.8 | 2.9 | 7.5 | 208.2 | 226 | 108 | 106 | 22 | 68 | 173 | 0 | 0 | 0 | 0 | 17 | 2 | 3 | 3.72 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 31 | 31 | 3 | 21 | 6.51 | .364 | 1.70 | 10.7 | 4.7 | 4.3 | 197.2 | 234 | 147 | 143 | 25 | 102 | 95 | 2 | 0 | 0 | 0 | 7 | 4 | 9 | 5.30 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 63 | 0 | 8 | 5 | 6.28 | .371 | 1.77 | 13.6 | 2.4 | 7.8 | 67.1 | 101 | 49 | 47 | 7 | 18 | 58 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 3.43 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 48 | 0 | 3 | 5 | 4.80 | .332 | 1.49 | 10.2 | 3.3 | 8.7 | 54.1 | 61 | 32 | 29 | 11 | 20 | 52 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 4.83 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 32 | 0 | 3 | 2 | 4.31 | .279 | 1.13 | 6.0 | 4.4 | 9.2 | 39.2 | 26 | 23 | 19 | 6 | 19 | 40 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.49 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 7 | 0 | 1 | 0 | 6.57 | .339 | 1.54 | 11.3 | 3.0 | 8.3 | 12.1 | 15 | 10 | 9 | 0 | 4 | 11 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 2.17 |