| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 22 | 22 | 9 | 7 | 4.56 | .319 | 1.39 | 9.2 | 3.3 | 8.6 | 146.0 | 150 | 75 | 74 | 14 | 53 | 140 | 1 | 0 | 0 | 0 | 10 | 2 | 2 | 3.46 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 21 | 21 | 9 | 9 | 5.26 | .348 | 1.59 | 8.4 | 6.0 | 7.1 | 126.2 | 118 | 74 | 74 | 17 | 84 | 100 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 5.19 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 71 | 21 | 21 | 12 | 5 | 3.64 | .297 | 1.25 | 9.2 | 2.1 | 4.7 | 173.0 | 177 | 70 | 70 | 20 | 40 | 91 | 11 | 0 | 0 | 0 | 13 | 2 | 3 | 4.18 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 21 | 21 | 5 | 12 | 6.10 | .342 | 1.54 | 10.9 | 3.0 | 4.4 | 149.0 | 180 | 105 | 101 | 12 | 49 | 73 | 5 | 0 | 0 | 0 | 6 | 3 | 3 | 4.11 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 57 | 0 | 3 | 2 | 3.64 | .283 | 1.17 | 7.5 | 3.2 | 9.1 | 71.2 | 59 | 30 | 29 | 7 | 25 | 72 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 3.35 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 30 | 0 | 3 | 2 | 3.06 | .303 | 1.30 | 9.3 | 2.6 | 5.7 | 35.1 | 36 | 14 | 12 | 4 | 10 | 22 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.09 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 18 | 0 | 3 | 1 | 6.75 | .422 | 2.19 | 11.8 | 7.9 | 6.8 | 16.0 | 21 | 12 | 12 | 1 | 14 | 12 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.94 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 2 | 0 | 0 | 0 | 0.00 | .273 | 1.13 | 9.0 | 4.5 | 13.5 | 2.2 | 2 | 0 | 0 | 0 | 1 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1.50 |