| SP | Arrieta, J.Arrieta, Jake $ >> | 29 | 2015 | R | 92 | 32 | 32 | 12 | 17 | 4.77 | .314 | 1.36 | 9.7 | 2.6 | 8.6 | 188.2 | 202 | 107 | 100 | 23 | 54 | 180 | 2 | 0 | 0 | 0 | 16 | 3 | 2 | 3.59 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 32 | 30 | 13 | 15 | 4.52 | .308 | 1.32 | 8.5 | 3.4 | 5.2 | 201.0 | 190 | 109 | 101 | 23 | 76 | 117 | 5 | 0 | 0 | 1 | 13 | 3 | 7 | 4.50 |
| SP | Hearn, J.Hearn, Jim # $$ >> | 29 | 1950 | R | 76 | 31 | 28 | 11 | 7 | 4.37 | .289 | 1.21 | 7.5 | 3.4 | 4.7 | 175.0 | 145 | 92 | 85 | 24 | 66 | 91 | 0 | 0 | 0 | 0 | 13 | 2 | 2 | 4.91 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 28 | 27 | 6 | 11 | 5.15 | .347 | 1.57 | 9.7 | 4.5 | 4.5 | 146.2 | 157 | 89 | 84 | 17 | 73 | 73 | 1 | 0 | 0 | 0 | 12 | 4 | 3 | 5.10 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 63 | 0 | 1 | 5 | 3.10 | .306 | 1.29 | 7.3 | 4.4 | 10.2 | 69.2 | 56 | 24 | 24 | 6 | 34 | 78 | 0 | 3 | 3 | 0 | 0 | 2 | 0 | 3.43 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 67 | 0 | 2 | 5 | 3.46 | .318 | 1.35 | 6.1 | 6.1 | 10.9 | 65.0 | 44 | 25 | 25 | 5 | 44 | 79 | 0 | 8 | 3 | 0 | 0 | 3 | 6 | 3.74 |
| RP | Rivera, M.Rivera, Mariano # >> | 39 | 2008 | R | 85 | 39 | 0 | 0 | 5 | 4.91 | .278 | 1.15 | 8.8 | 1.7 | 8.0 | 47.2 | 46 | 27 | 26 | 4 | 9 | 42 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 2.89 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 29 | 5 | 4 | 1 | 4.53 | .315 | 1.36 | 8.5 | 3.8 | 5.6 | 107.1 | 101 | 58 | 54 | 17 | 45 | 66 | 0 | 0 | 0 | 0 | 2 | 2 | 4 | 5.15 |