| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 96 | 22 | 22 | 9 | 10 | 3.80 | .274 | 1.12 | 8.1 | 2.0 | 6.7 | 135.0 | 121 | 57 | 57 | 16 | 30 | 100 | 1 | 0 | 0 | 1 | 13 | 2 | 0 | 3.77 |
| SP | Halladay, R.Halladay, Roy >> | 24 | 2001 | R | 80 | 22 | 22 | 7 | 7 | 4.93 | .329 | 1.43 | 9.9 | 3.0 | 5.6 | 126.0 | 138 | 72 | 69 | 18 | 42 | 79 | 0 | 0 | 0 | 0 | 11 | 5 | 4 | 4.72 |
| SP | Radke, B.Radke, Brad # >> | 29 | 2001 | R | 57 | 21 | 21 | 8 | 5 | 4.50 | .309 | 1.32 | 9.8 | 2.1 | 6.4 | 130.0 | 141 | 68 | 65 | 12 | 30 | 92 | 0 | 0 | 0 | 0 | 8 | 3 | 1 | 3.55 |
| SP | Colon, B.Colon, Bartolo >> | 28 | 2001 | R | 40 | 22 | 20 | 7 | 6 | 5.10 | .351 | 1.58 | 10.8 | 3.5 | 6.9 | 118.1 | 141 | 73 | 67 | 12 | 46 | 90 | 0 | 0 | 0 | 0 | 8 | 5 | 0 | 4.09 |
| CL | Rivera, M.Rivera, Mariano >> | 32 | 2001 | R | 93 | 35 | 0 | 6 | 9 | 6.31 | .318 | 1.37 | 9.8 | 2.8 | 8.2 | 35.2 | 38 | 25 | 25 | 6 | 11 | 32 | 0 | 12 | 4 | 0 | 0 | 1 | 0 | 4.43 |
| RP | Charlton, N.Charlton, Norm >> | 38 | 2001 | L | 89 | 38 | 0 | 0 | 1 | 4.21 | .369 | 1.71 | 11.5 | 4.3 | 7.9 | 25.2 | 32 | 13 | 12 | 3 | 12 | 22 | 0 | 2 | 1 | 0 | 0 | 1 | 3 | 4.36 |
| RP | Arrojo, R.Arrojo, Rolando >> | 33 | 2001 | R | 68 | 43 | 0 | 3 | 2 | 4.30 | .316 | 1.36 | 8.0 | 4.3 | 5.7 | 44.0 | 39 | 21 | 21 | 7 | 21 | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.30 |
| RP | Dotel, O.Dotel, Octavio >> | 28 | 2001 | R | 79 | 43 | 0 | 0 | 2 | 4.74 | .341 | 1.55 | 9.7 | 4.3 | 11.4 | 38.0 | 41 | 21 | 20 | 6 | 18 | 48 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.95 |
| RP | Looper, B.Looper, Braden >> | 27 | 2001 | R | 41 | 11 | 0 | 0 | 0 | 9.00 | .415 | 2.13 | 16.9 | 2.3 | 6.8 | 8.0 | 15 | 8 | 8 | 3 | 2 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.13 |
| RP | Stanton, M.Stanton, Mike >> | 34 | 2001 | L | 23 | 48 | 0 | 1 | 1 | 5.77 | .352 | 1.57 | 10.3 | 4.0 | 5.0 | 34.1 | 39 | 22 | 22 | 8 | 15 | 19 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 6.44 |