| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 93 | 31 | 31 | 17 | 9 | 3.35 | .267 | 1.08 | 7.0 | 2.7 | 6.9 | 223.0 | 173 | 85 | 83 | 28 | 68 | 172 | 8 | 0 | 0 | 1 | 20 | 3 | 5 | 4.04 |
| SP | Johnson, R.Johnson, Randy † >> | 41 | 2004 | L | 90 | 30 | 30 | 13 | 7 | 5.10 | .298 | 1.25 | 8.6 | 2.7 | 8.9 | 180.0 | 171 | 104 | 102 | 30 | 54 | 177 | 4 | 0 | 0 | 1 | 11 | 4 | 2 | 4.17 |
| SP | Tanana, F.Tanana, Frank # >> | 23 | 1976 | L | 73 | 30 | 30 | 11 | 9 | 4.78 | .321 | 1.41 | 9.6 | 3.1 | 6.5 | 196.0 | 210 | 111 | 104 | 32 | 67 | 142 | 7 | 0 | 0 | 1 | 12 | 1 | 3 | 4.71 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 88 | 69 | 0 | 4 | 6 | 4.28 | .322 | 1.40 | 7.3 | 5.4 | 8.9 | 73.2 | 59 | 35 | 35 | 12 | 44 | 72 | 0 | 6 | 2 | 0 | 0 | 2 | 2 | 5.05 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 53 | 0 | 3 | 4 | 3.27 | .274 | 1.13 | 7.7 | 2.5 | 8.9 | 77.0 | 66 | 31 | 28 | 3 | 21 | 76 | 0 | 6 | 2 | 0 | 0 | 0 | 0 | 2.35 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 82 | 43 | 0 | 3 | 2 | 5.47 | .354 | 1.64 | 8.6 | 6.2 | 9.4 | 49.1 | 47 | 31 | 30 | 4 | 34 | 51 | 0 | 6 | 3 | 0 | 0 | 0 | 0 | 4.06 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 26 | 0 | 3 | 0 | 1.24 | .298 | 1.28 | 6.8 | 4.7 | 11.5 | 29.0 | 22 | 4 | 4 | 2 | 15 | 37 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 2.90 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 76 | 26 | 0 | 1 | 1 | 3.69 | .275 | 1.11 | 7.0 | 3.2 | 5.5 | 31.2 | 24 | 13 | 13 | 3 | 11 | 19 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.19 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 27 | 0 | 1 | 2 | 4.50 | .338 | 1.50 | 8.4 | 5.1 | 10.4 | 32.0 | 30 | 16 | 16 | 5 | 18 | 37 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.50 |