| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 24 | 24 | 7 | 9 | 4.08 | .306 | 1.31 | 8.9 | 2.9 | 9.7 | 183.0 | 181 | 88 | 83 | 23 | 58 | 198 | 6 | 0 | 0 | 1 | 12 | 3 | 4 | 3.47 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 84 | 23 | 23 | 9 | 10 | 5.29 | .322 | 1.40 | 8.9 | 3.8 | 5.2 | 161.2 | 159 | 95 | 95 | 28 | 68 | 93 | 5 | 0 | 0 | 0 | 11 | 3 | 3 | 5.43 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 69 | 23 | 23 | 7 | 8 | 4.12 | .303 | 1.29 | 8.3 | 3.4 | 7.2 | 146.1 | 134 | 69 | 67 | 19 | 55 | 116 | 0 | 0 | 0 | 0 | 12 | 2 | 4 | 4.27 |
| SP | Higuera, T.Higuera, Teddy # >> | 30 | 1988 | L | 63 | 23 | 23 | 14 | 7 | 3.49 | .287 | 1.20 | 7.8 | 3.1 | 6.7 | 173.0 | 149 | 77 | 67 | 27 | 59 | 129 | 6 | 0 | 0 | 3 | 14 | 1 | 0 | 4.58 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 55 | 21 | 21 | 5 | 11 | 4.99 | .324 | 1.39 | 8.9 | 3.7 | 6.1 | 137.0 | 135 | 79 | 76 | 24 | 56 | 93 | 1 | 0 | 0 | 0 | 10 | 6 | 2 | 5.28 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 64 | 0 | 2 | 6 | 3.91 | .275 | 1.10 | 6.9 | 3.0 | 10.0 | 78.1 | 60 | 34 | 34 | 7 | 26 | 87 | 0 | 7 | 2 | 0 | 0 | 3 | 1 | 3.05 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 45 | 0 | 3 | 3 | 6.28 | .355 | 1.60 | 10.9 | 3.6 | 8.2 | 43.0 | 52 | 30 | 30 | 6 | 17 | 39 | 0 | 5 | 3 | 0 | 0 | 2 | 0 | 4.33 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 68 | 31 | 0 | 3 | 1 | 3.35 | .284 | 1.17 | 7.7 | 2.9 | 9.7 | 40.1 | 34 | 17 | 15 | 5 | 13 | 43 | 0 | 5 | 2 | 0 | 0 | 1 | 0 | 3.53 |
| RP | Pressly, R.Pressly, Ryan >> | 30 | 2019 | R | 53 | 24 | 0 | 1 | 2 | 5.13 | .301 | 1.25 | 9.3 | 2.1 | 9.0 | 26.1 | 27 | 15 | 15 | 6 | 6 | 26 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.81 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 51 | 9 | 0 | 0 | 2 | 7.62 | .391 | 1.85 | 12.5 | 4.2 | 6.2 | 13.0 | 18 | 11 | 11 | 0 | 6 | 9 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.23 |