| SP | deGrom, J.deGrom, Jacob $$ >> | 33 | 2021 | R | 100 | 27 | 27 | 10 | 13 | 3.93 | .290 | 1.20 | 8.0 | 2.9 | 10.5 | 162.2 | 144 | 75 | 71 | 16 | 52 | 189 | 0 | 0 | 0 | 0 | 17 | 3 | 0 | 2.97 |
| SP | Scherzer, M.Scherzer, Max $$ >> | 33 | 2017 | R | 95 | 26 | 26 | 7 | 12 | 4.56 | .313 | 1.36 | 7.6 | 4.6 | 8.4 | 160.0 | 135 | 82 | 81 | 20 | 82 | 150 | 1 | 0 | 0 | 0 | 15 | 2 | 2 | 4.33 |
| SP | Kluber, C.Kluber, Corey $ >> | 31 | 2017 | R | 89 | 25 | 25 | 5 | 15 | 4.70 | .341 | 1.55 | 10.1 | 3.8 | 9.3 | 159.0 | 178 | 87 | 83 | 19 | 68 | 165 | 0 | 0 | 0 | 0 | 13 | 1 | 2 | 3.78 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 24 | 24 | 8 | 8 | 4.90 | .348 | 1.56 | 10.1 | 4.1 | 4.7 | 161.2 | 180 | 96 | 88 | 20 | 73 | 84 | 3 | 0 | 0 | 0 | 11 | 6 | 5 | 5.04 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 45 | 0 | 4 | 7 | 3.94 | .290 | 1.20 | 6.6 | 4.4 | 11.0 | 45.2 | 33 | 20 | 20 | 7 | 22 | 55 | 0 | 23 | 2 | 0 | 0 | 1 | 0 | 4.11 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 65 | 0 | 4 | 2 | 3.84 | .306 | 1.25 | 8.0 | 3.4 | 9.0 | 72.2 | 64 | 34 | 31 | 9 | 27 | 72 | 0 | 0 | 3 | 0 | 0 | 5 | 2 | 3.96 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 44 | 0 | 4 | 3 | 5.44 | .341 | 1.53 | 10.4 | 3.5 | 8.0 | 46.1 | 53 | 30 | 28 | 10 | 18 | 41 | 0 | 1 | 4 | 0 | 0 | 1 | 2 | 5.28 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 41 | 0 | 1 | 1 | 5.29 | .357 | 1.64 | 10.8 | 4.0 | 8.4 | 49.1 | 59 | 31 | 29 | 6 | 22 | 46 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.12 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |