| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 25 | 25 | 8 | 12 | 4.28 | .284 | 1.17 | 7.9 | 2.6 | 9.2 | 160.0 | 141 | 77 | 76 | 18 | 46 | 164 | 0 | 0 | 0 | 0 | 13 | 3 | 0 | 3.33 |
| SP | Scherzer, M.Scherzer, Max $ >> | 33 | 2017 | R | 95 | 24 | 24 | 7 | 9 | 4.62 | .315 | 1.34 | 8.1 | 4.0 | 7.4 | 150.0 | 135 | 79 | 77 | 16 | 66 | 123 | 0 | 0 | 0 | 0 | 12 | 6 | 6 | 4.19 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 23 | 23 | 9 | 8 | 4.97 | .327 | 1.46 | 9.5 | 3.7 | 9.1 | 150.1 | 158 | 84 | 83 | 22 | 61 | 152 | 0 | 0 | 0 | 0 | 12 | 0 | 2 | 4.10 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 51 | 0 | 5 | 4 | 3.73 | .283 | 1.16 | 6.3 | 4.3 | 8.8 | 50.2 | 35 | 22 | 21 | 6 | 24 | 49 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 4.10 |
| SU | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 37 | 0 | 1 | 0 | 1.13 | .231 | 0.85 | 4.1 | 3.6 | 7.4 | 40.0 | 18 | 5 | 5 | 1 | 16 | 33 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 3.03 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 35 | 0 | 4 | 0 | 2.00 | .224 | 0.87 | 5.0 | 2.8 | 7.2 | 45.0 | 25 | 11 | 10 | 2 | 14 | 36 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.91 |