| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 26 | 26 | 10 | 13 | 3.89 | .308 | 1.31 | 9.1 | 2.7 | 5.7 | 194.1 | 196 | 90 | 84 | 16 | 59 | 122 | 9 | 0 | 0 | 2 | 16 | 5 | 4 | 3.80 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 24 | 24 | 4 | 13 | 6.11 | .352 | 1.59 | 10.7 | 3.6 | 8.3 | 150.1 | 179 | 109 | 102 | 26 | 60 | 139 | 2 | 0 | 0 | 0 | 8 | 6 | 5 | 4.72 |
| SP | Coveleski, S.Coveleski, Stan # >> | 28 | 1917 | R | 62 | 24 | 24 | 8 | 11 | 4.95 | .316 | 1.37 | 8.7 | 3.7 | 4.4 | 161.2 | 156 | 98 | 89 | 20 | 66 | 78 | 3 | 0 | 0 | 0 | 11 | 2 | 5 | 4.91 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 23 | 23 | 5 | 12 | 5.92 | .360 | 1.66 | 12.0 | 2.9 | 4.4 | 155.0 | 207 | 107 | 102 | 22 | 50 | 75 | 4 | 0 | 0 | 0 | 5 | 5 | 6 | 4.94 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 62 | 0 | 5 | 5 | 4.78 | .340 | 1.53 | 8.4 | 5.4 | 7.4 | 79.0 | 74 | 51 | 42 | 13 | 47 | 65 | 0 | 4 | 6 | 0 | 0 | 1 | 3 | 5.32 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 56 | 0 | 1 | 2 | 4.23 | .274 | 1.09 | 7.5 | 2.4 | 7.8 | 72.1 | 60 | 38 | 34 | 12 | 19 | 62 | 0 | 3 | 1 | 0 | 0 | 3 | 0 | 4.36 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 54 | 34 | 0 | 3 | 0 | 2.86 | .298 | 1.25 | 6.5 | 4.7 | 8.8 | 44.0 | 32 | 14 | 14 | 1 | 23 | 43 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 2.98 |
| SP | Cooper, M.Cooper, Mort >> | 29 | 1942 | R | 47 | 3 | 0 | 1 | 0 | 1.23 | .154 | 0.55 | 5.1 | 0.0 | 1.3 | 7.1 | 4 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.57 |