| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 25 | 25 | 9 | 6 | 3.84 | .277 | 1.14 | 7.8 | 2.5 | 5.8 | 183.0 | 158 | 78 | 78 | 18 | 50 | 118 | 2 | 0 | 0 | 1 | 16 | 2 | 2 | 3.84 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 81 | 24 | 24 | 8 | 5 | 4.12 | .311 | 1.32 | 7.8 | 4.1 | 8.5 | 146.1 | 126 | 75 | 67 | 19 | 67 | 138 | 0 | 0 | 0 | 0 | 10 | 5 | 7 | 4.28 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 23 | 23 | 6 | 12 | 5.75 | .320 | 1.40 | 9.5 | 3.1 | 5.1 | 153.1 | 162 | 100 | 98 | 28 | 52 | 86 | 5 | 0 | 0 | 0 | 10 | 2 | 1 | 5.31 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 23 | 23 | 6 | 12 | 6.66 | .371 | 1.72 | 10.9 | 4.6 | 5.3 | 128.1 | 155 | 101 | 95 | 23 | 66 | 75 | 0 | 0 | 0 | 0 | 7 | 6 | 3 | 5.85 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 56 | 0 | 5 | 9 | 2.89 | .323 | 1.43 | 6.5 | 6.5 | 10.9 | 53.0 | 38 | 17 | 17 | 1 | 38 | 64 | 0 | 29 | 3 | 0 | 0 | 0 | 6 | 2.98 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 65 | 0 | 7 | 0 | 3.26 | .252 | 1.01 | 6.0 | 3.2 | 9.4 | 77.1 | 51 | 29 | 28 | 6 | 27 | 80 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 2.99 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 36 | 0 | 3 | 2 | 3.20 | .337 | 1.50 | 8.1 | 5.5 | 7.8 | 39.1 | 35 | 21 | 14 | 5 | 24 | 34 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 4.85 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 28 | 0 | 2 | 3 | 3.90 | .287 | 1.21 | 7.0 | 3.9 | 8.4 | 32.1 | 25 | 14 | 14 | 3 | 14 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.66 |