| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 4 | 4 | 3 | 1 | 2.05 | .275 | 1.14 | 8.3 | 2.1 | 3.8 | 26.1 | 24 | 9 | 6 | 2 | 6 | 11 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 3.85 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 4 | 4 | 2 | 1 | 1.03 | .275 | 1.10 | 6.2 | 3.8 | 2.8 | 26.1 | 18 | 11 | 3 | 0 | 11 | 8 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 3.77 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 3 | 3 | 2 | 0 | 1.69 | .297 | 1.27 | 8.6 | 3.0 | 9.4 | 21.1 | 20 | 4 | 4 | 0 | 7 | 22 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 1.90 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 11 | 0 | 0 | 0 | 4.91 | .365 | 1.73 | 13.1 | 2.5 | 9.0 | 11.0 | 16 | 6 | 6 | 1 | 3 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.00 |
| CL | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 8 | 0 | 1 | 1 | 6.75 | .273 | 1.00 | 7.9 | 1.1 | 7.9 | 8.0 | 7 | 6 | 6 | 1 | 1 | 7 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 3.63 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 8 | 0 | 0 | 0 | 9.82 | .421 | 1.91 | 15.0 | 6.0 | 6.0 | 3.2 | 5 | 4 | 4 | 2 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 13.33 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 44 | 7 | 0 | 0 | 0 | 1.80 | .211 | 0.80 | 7.2 | 0.0 | 0.0 | 5.0 | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.60 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 5 | 0 | 0 | 0 | 0.00 | .154 | 0.55 | 6.0 | 0.0 | 9.0 | 3.2 | 2 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 2 | 0 | 1 | 0 | 6.00 | .250 | 1.00 | 9.0 | 0.0 | 12.0 | 3.0 | 3 | 2 | 2 | 1 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.67 |