| SP | Koufax, S.Koufax, Sandy † # >> | 30 | 1965 | L | 97 | 23 | 23 | 10 | 7 | 3.52 | .294 | 1.23 | 7.9 | 3.2 | 7.6 | 166.1 | 145 | 67 | 65 | 16 | 59 | 140 | 4 | 0 | 0 | 1 | 14 | 4 | 3 | 3.70 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 22 | 22 | 3 | 6 | 5.92 | .345 | 1.56 | 10.2 | 4.0 | 4.8 | 86.2 | 97 | 57 | 57 | 14 | 38 | 46 | 0 | 0 | 0 | 0 | 2 | 2 | 4 | 5.44 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 63 | 19 | 17 | 8 | 6 | 4.79 | .313 | 1.32 | 9.6 | 2.4 | 4.7 | 99.2 | 106 | 58 | 53 | 14 | 26 | 52 | 1 | 0 | 0 | 0 | 6 | 4 | 1 | 4.70 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 23 | 20 | 4 | 12 | 5.87 | .355 | 1.60 | 9.6 | 4.9 | 4.2 | 110.1 | 117 | 79 | 72 | 15 | 60 | 51 | 0 | 0 | 0 | 0 | 4 | 5 | 2 | 5.62 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 50 | 0 | 3 | 4 | 2.86 | .286 | 1.16 | 5.9 | 4.7 | 7.6 | 56.2 | 37 | 18 | 18 | 5 | 29 | 47 | 0 | 6 | 1 | 0 | 0 | 2 | 0 | 4.14 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 43 | 0 | 2 | 3 | 3.77 | .299 | 1.28 | 6.7 | 4.8 | 10.0 | 43.0 | 32 | 19 | 18 | 2 | 23 | 48 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 2.98 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 53 | 0 | 1 | 1 | 4.21 | .329 | 1.43 | 9.4 | 3.4 | 7.3 | 47.0 | 49 | 23 | 22 | 9 | 18 | 38 | 0 | 2 | 3 | 0 | 0 | 2 | 1 | 5.15 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 41 | 0 | 3 | 4 | 4.93 | .335 | 1.51 | 10.2 | 3.6 | 10.7 | 38.1 | 43 | 21 | 21 | 5 | 15 | 45 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 3.53 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 26 | 4 | 4 | 3 | 6.35 | .341 | 1.53 | 10.0 | 3.9 | 8.8 | 90.2 | 100 | 68 | 64 | 11 | 39 | 88 | 0 | 1 | 0 | 0 | 1 | 2 | 5 | 4.00 |