| SP | Scherzer, M.Scherzer, Max $$ >> | 33 | 2017 | R | 95 | 34 | 34 | 11 | 14 | 4.04 | .322 | 1.41 | 8.4 | 4.3 | 8.5 | 216.1 | 201 | 113 | 97 | 28 | 103 | 204 | 0 | 0 | 0 | 0 | 18 | 4 | 1 | 4.28 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 33 | 33 | 11 | 16 | 4.12 | .304 | 1.29 | 9.5 | 2.1 | 6.2 | 231.1 | 243 | 118 | 106 | 27 | 55 | 160 | 8 | 0 | 0 | 3 | 17 | 5 | 2 | 3.91 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 85 | 32 | 32 | 10 | 11 | 4.66 | .325 | 1.44 | 10.0 | 3.1 | 8.3 | 179.2 | 198 | 101 | 93 | 21 | 61 | 165 | 1 | 0 | 0 | 0 | 17 | 1 | 6 | 3.72 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 32 | 32 | 6 | 16 | 5.26 | .337 | 1.52 | 11.1 | 2.7 | 5.0 | 162.2 | 200 | 112 | 95 | 21 | 48 | 90 | 0 | 0 | 0 | 0 | 7 | 0 | 4 | 4.46 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 31 | 31 | 8 | 16 | 5.41 | .334 | 1.50 | 9.3 | 4.2 | 5.6 | 209.2 | 216 | 143 | 126 | 28 | 98 | 130 | 1 | 0 | 0 | 0 | 11 | 2 | 5 | 4.93 |
| CL | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 57 | 0 | 3 | 6 | 4.72 | .327 | 1.44 | 8.0 | 5.0 | 7.2 | 61.0 | 54 | 33 | 32 | 7 | 34 | 49 | 0 | 28 | 5 | 0 | 0 | 1 | 2 | 4.61 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 72 | 0 | 3 | 10 | 2.92 | .265 | 1.05 | 6.1 | 3.4 | 8.6 | 92.1 | 62 | 34 | 30 | 5 | 35 | 88 | 0 | 6 | 10 | 0 | 0 | 3 | 1 | 3.03 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 60 | 0 | 2 | 0 | 5.01 | .363 | 1.67 | 9.7 | 5.6 | 9.3 | 55.2 | 59 | 38 | 31 | 10 | 34 | 57 | 0 | 0 | 2 | 0 | 0 | 2 | 4 | 5.25 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 46 | 0 | 0 | 3 | 5.32 | .380 | 1.82 | 11.1 | 5.4 | 10.1 | 47.1 | 58 | 32 | 28 | 5 | 28 | 53 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 3.98 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 19 | 0 | 2 | 5 | 8.63 | .395 | 1.96 | 12.6 | 5.1 | 3.4 | 48.0 | 67 | 49 | 46 | 11 | 27 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 6.92 |