| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 7 | 7 | 2 | 4 | 2.91 | .291 | 1.23 | 6.7 | 4.5 | 6.8 | 46.1 | 34 | 21 | 15 | 5 | 23 | 35 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 4.39 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 7 | 7 | 2 | 4 | 6.39 | .364 | 1.69 | 13.0 | 2.5 | 7.3 | 43.2 | 62 | 34 | 31 | 6 | 12 | 35 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.09 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 6 | 6 | 3 | 0 | 2.83 | .309 | 1.31 | 9.3 | 2.6 | 9.3 | 35.0 | 36 | 11 | 11 | 2 | 10 | 36 | 0 | 0 | 0 | 0 | 5 | 1 | 2 | 2.63 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 6 | 6 | 2 | 2 | 4.24 | .311 | 1.35 | 10.9 | 1.3 | 6.6 | 34.0 | 41 | 17 | 16 | 2 | 5 | 25 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 2.74 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 6 | 6 | 1 | 4 | 4.71 | .344 | 1.55 | 9.4 | 4.5 | 3.9 | 42.0 | 44 | 24 | 22 | 5 | 21 | 18 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 5.26 |
| CL | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 12 | 0 | 2 | 1 | 2.31 | .255 | 1.03 | 7.4 | 2.5 | 8.2 | 11.2 | 9 | 3 | 3 | 1 | 3 | 10 | 0 | 9 | 0 | 0 | 0 | 0 | 0 | 3.18 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 14 | 0 | 1 | 1 | 3.86 | .222 | 0.86 | 4.0 | 4.0 | 11.5 | 18.2 | 8 | 8 | 8 | 2 | 8 | 23 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.22 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 11 | 0 | 1 | 0 | 3.86 | .314 | 1.37 | 9.8 | 3.3 | 7.4 | 11.2 | 12 | 6 | 5 | 3 | 4 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.00 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 9 | 0 | 0 | 0 | 4.50 | .318 | 1.40 | 9.9 | 2.7 | 9.0 | 10.0 | 11 | 5 | 5 | 2 | 3 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.50 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 1 | 0 | 0 | 1 | 15.75 | .455 | 2.50 | 18.0 | 4.5 | 0.0 | 4.0 | 8 | 7 | 7 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 7.75 |