| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 34 | 34 | 15 | 13 | 3.68 | .301 | 1.27 | 8.5 | 2.9 | 5.7 | 276.1 | 262 | 121 | 113 | 31 | 90 | 174 | 13 | 0 | 0 | 3 | 19 | 5 | 4 | 4.23 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 74 | 33 | 33 | 12 | 20 | 4.29 | .305 | 1.30 | 9.1 | 2.6 | 5.4 | 262.1 | 264 | 130 | 125 | 27 | 77 | 158 | 14 | 0 | 0 | 3 | 16 | 5 | 4 | 4.07 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 32 | 32 | 8 | 20 | 5.63 | .323 | 1.42 | 9.7 | 3.0 | 6.8 | 230.1 | 249 | 152 | 144 | 39 | 77 | 174 | 3 | 0 | 0 | 1 | 11 | 3 | 3 | 4.73 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 99 | 0 | 1 | 3 | 3.34 | .288 | 1.21 | 5.9 | 5.0 | 9.2 | 59.1 | 39 | 28 | 22 | 10 | 33 | 60 | 0 | 3 | 1 | 0 | 0 | 0 | 3 | 4.85 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 81 | 0 | 2 | 2 | 4.38 | .307 | 1.32 | 8.2 | 3.7 | 8.6 | 76.0 | 69 | 38 | 37 | 14 | 31 | 73 | 0 | 8 | 0 | 0 | 0 | 1 | 0 | 4.74 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 59 | 0 | 2 | 2 | 4.43 | .309 | 1.34 | 6.7 | 5.4 | 8.1 | 67.0 | 50 | 33 | 33 | 9 | 40 | 60 | 0 | 8 | 3 | 0 | 0 | 0 | 1 | 4.75 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 56 | 42 | 0 | 2 | 5 | 6.31 | .340 | 1.55 | 10.5 | 3.5 | 9.2 | 41.1 | 48 | 30 | 29 | 8 | 16 | 42 | 0 | 4 | 4 | 0 | 0 | 0 | 3 | 4.66 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 47 | 32 | 0 | 5 | 3 | 7.44 | .384 | 1.81 | 12.4 | 4.2 | 8.2 | 32.2 | 44 | 28 | 27 | 7 | 15 | 29 | 0 | 1 | 2 | 0 | 0 | 2 | 2 | 5.63 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 6 | 0 | 0 | 0 | 6.75 | .355 | 1.65 | 15.0 | 1.5 | 3.0 | 6.2 | 10 | 5 | 5 | 2 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.17 |