| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 7 | 7 | 1 | 4 | 6.55 | .348 | 1.57 | 11.4 | 2.9 | 6.4 | 34.1 | 43 | 30 | 25 | 2 | 11 | 24 | 1 | 0 | 0 | 0 | 2 | 1 | 1 | 3.41 |
| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 92 | 7 | 7 | 1 | 2 | 5.86 | .350 | 1.58 | 10.8 | 3.6 | 5.9 | 35.1 | 42 | 24 | 23 | 5 | 14 | 23 | 1 | 0 | 0 | 1 | 2 | 1 | 0 | 4.83 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 6 | 6 | 1 | 2 | 5.73 | .331 | 1.45 | 10.6 | 2.5 | 6.5 | 33.0 | 39 | 22 | 21 | 7 | 9 | 24 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 5.21 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 6 | 6 | 2 | 1 | 4.69 | .309 | 1.31 | 7.4 | 4.5 | 6.3 | 40.1 | 33 | 22 | 21 | 6 | 20 | 28 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 5.13 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 7 | 6 | 3 | 2 | 6.50 | .400 | 2.00 | 12.0 | 6.0 | 4.3 | 36.0 | 48 | 29 | 26 | 4 | 24 | 17 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 5.50 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 16 | 0 | 3 | 1 | 2.37 | .219 | 0.84 | 5.7 | 1.9 | 8.5 | 19.0 | 12 | 5 | 5 | 1 | 4 | 18 | 0 | 5 | 1 | 0 | 0 | 0 | 4 | 2.42 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 20 | 0 | 0 | 1 | 2.55 | .221 | 0.81 | 7.1 | 0.4 | 7.5 | 24.2 | 19 | 8 | 7 | 1 | 1 | 20 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 2.13 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 19 | 0 | 2 | 3 | 5.40 | .306 | 1.32 | 6.5 | 5.4 | 10.4 | 25.0 | 18 | 16 | 15 | 2 | 15 | 29 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.52 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 21 | 0 | 0 | 1 | 2.49 | .278 | 1.15 | 5.6 | 5.1 | 5.6 | 21.2 | 13 | 6 | 6 | 2 | 12 | 13 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.71 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 75 | 16 | 0 | 1 | 1 | 8.14 | .406 | 2.00 | 15.0 | 3.0 | 10.3 | 21.0 | 35 | 21 | 19 | 4 | 7 | 24 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.33 |