| SP | Tiant, L.Tiant, Luis $$ >> | 28 | 1968 | R | 97 | 20 | 20 | 10 | 6 | 3.90 | .305 | 1.31 | 7.7 | 4.0 | 7.6 | 127.0 | 109 | 60 | 55 | 12 | 57 | 107 | 2 | 0 | 0 | 1 | 14 | 1 | 1 | 3.91 |
| SP | Alexander, P.Alexander, Pete # $$ >> | 28 | 1915 | R | 88 | 19 | 19 | 8 | 5 | 3.98 | .299 | 1.26 | 8.7 | 2.7 | 5.7 | 129.0 | 124 | 66 | 57 | 18 | 38 | 82 | 2 | 0 | 0 | 0 | 9 | 3 | 2 | 4.50 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 18 | 18 | 4 | 7 | 4.15 | .314 | 1.35 | 9.0 | 3.2 | 5.3 | 95.1 | 95 | 44 | 44 | 12 | 34 | 56 | 0 | 0 | 0 | 0 | 6 | 2 | 3 | 4.60 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 47 | 0 | 4 | 0 | 4.65 | .348 | 1.53 | 8.9 | 5.0 | 8.0 | 60.0 | 59 | 31 | 31 | 6 | 33 | 53 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 4.38 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 45 | 0 | 4 | 2 | 4.01 | .289 | 1.20 | 9.0 | 2.0 | 8.7 | 60.2 | 60 | 31 | 27 | 6 | 13 | 58 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.07 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 41 | 0 | 2 | 5 | 4.03 | .280 | 1.16 | 7.6 | 3.1 | 9.0 | 44.2 | 37 | 20 | 20 | 5 | 15 | 44 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 3.50 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 30 | 0 | 1 | 0 | 5.06 | .364 | 1.72 | 9.8 | 5.6 | 8.2 | 32.0 | 35 | 18 | 18 | 3 | 20 | 29 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.28 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 15 | 0 | 1 | 2 | 7.66 | .412 | 2.10 | 14.7 | 4.5 | 6.5 | 22.1 | 36 | 24 | 19 | 3 | 11 | 16 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.82 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 46 | 0 | 2 | 4 | 7.83 | .379 | 1.81 | 9.8 | 6.7 | 9.0 | 43.2 | 47 | 38 | 38 | 9 | 32 | 43 | 0 | 15 | 5 | 0 | 0 | 1 | 1 | 6.02 |