| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 6 | 6 | 3 | 1 | 3.76 | .311 | 1.25 | 7.2 | 4.3 | 7.4 | 40.2 | 32 | 17 | 17 | 4 | 19 | 33 | 1 | 0 | 0 | 1 | 3 | 4 | 0 | 4.38 |
| SP | Alvarez, W.Alvarez, Wilson # >> | 33 | 2003 | L | 73 | 6 | 6 | 0 | 3 | 5.02 | .353 | 1.64 | 11.9 | 3.2 | 7.1 | 28.2 | 37 | 19 | 16 | 6 | 10 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.29 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 61 | 6 | 6 | 1 | 4 | 4.47 | .318 | 1.38 | 9.2 | 3.3 | 5.9 | 44.1 | 45 | 22 | 22 | 4 | 16 | 29 | 2 | 0 | 0 | 0 | 3 | 1 | 1 | 4.02 |
| SP | Harang, A.Harang, Aaron >> | 29 | 2007 | R | 51 | 6 | 6 | 1 | 4 | 9.91 | .410 | 2.05 | 14.5 | 4.2 | 5.2 | 26.1 | 42 | 29 | 29 | 12 | 12 | 15 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 9.35 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 47 | 6 | 6 | 1 | 4 | 8.70 | .371 | 1.73 | 10.8 | 4.8 | 7.2 | 30.0 | 36 | 29 | 29 | 7 | 16 | 24 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 6.13 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 15 | 0 | 1 | 1 | 5.01 | .293 | 1.24 | 7.8 | 3.5 | 10.2 | 23.1 | 20 | 13 | 13 | 4 | 9 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.17 |
| RP | Timlin, M.Timlin, Mike >> | 36 | 2002 | R | 50 | 14 | 0 | 0 | 0 | 1.47 | .203 | 0.76 | 3.5 | 3.5 | 7.0 | 18.1 | 7 | 3 | 3 | 1 | 7 | 14 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 3.33 |
| RP | Aardsma, D.Aardsma, David >> | 28 | 2009 | R | 36 | 8 | 0 | 1 | 0 | 7.84 | .380 | 1.84 | 11.7 | 5.4 | 3.6 | 10.1 | 13 | 9 | 9 | 4 | 6 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.20 |
| SP | Person, R.Person, Robert >> | 32 | 2001 | R | 26 | 9 | 0 | 0 | 1 | 6.61 | .300 | 1.29 | 7.3 | 4.5 | 4.5 | 16.1 | 13 | 12 | 12 | 3 | 8 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.94 |