| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 19 | 19 | 6 | 10 | 4.82 | .306 | 1.30 | 7.5 | 4.2 | 8.5 | 114.0 | 95 | 67 | 61 | 15 | 53 | 108 | 0 | 0 | 0 | 0 | 10 | 3 | 2 | 4.29 |
| SP | Buehrle, M.Buehrle, Mark # >> | 22 | 2001 | L | 67 | 17 | 17 | 5 | 7 | 5.56 | .314 | 1.34 | 9.9 | 2.3 | 5.4 | 111.2 | 122 | 74 | 69 | 17 | 28 | 67 | 1 | 0 | 0 | 0 | 7 | 3 | 0 | 4.62 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 56 | 15 | 15 | 3 | 8 | 8.17 | .377 | 1.78 | 12.4 | 3.6 | 7.3 | 79.1 | 109 | 73 | 72 | 20 | 32 | 64 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 6.00 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 69 | 48 | 0 | 1 | 1 | 4.47 | .311 | 1.30 | 9.0 | 2.8 | 9.6 | 58.1 | 58 | 32 | 29 | 9 | 18 | 62 | 0 | 3 | 1 | 0 | 0 | 3 | 0 | 3.97 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 50 | 45 | 0 | 1 | 5 | 3.21 | .323 | 1.38 | 8.2 | 4.2 | 7.7 | 56.0 | 51 | 20 | 20 | 6 | 26 | 48 | 0 | 5 | 2 | 0 | 0 | 3 | 0 | 4.23 |
| RP | Kim, B.Kim, Byung-Hyun >> | 23 | 2002 | R | 36 | 35 | 0 | 3 | 1 | 2.18 | .303 | 1.28 | 8.3 | 3.3 | 10.1 | 41.1 | 38 | 10 | 10 | 5 | 15 | 46 | 0 | 4 | 0 | 0 | 0 | 1 | 2 | 3.51 |
| RP | Corpas, M.Corpas, Manuel >> | 25 | 2007 | R | 25 | 31 | 0 | 0 | 2 | 3.15 | .302 | 1.30 | 9.5 | 2.3 | 9.0 | 40.0 | 42 | 15 | 14 | 5 | 10 | 40 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.38 |