| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 98 | 26 | 26 | 5 | 7 | 5.51 | .347 | 1.55 | 10.5 | 3.5 | 8.5 | 114.1 | 133 | 73 | 70 | 22 | 44 | 108 | 0 | 0 | 0 | 0 | 2 | 5 | 6 | 4.90 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 85 | 26 | 26 | 2 | 10 | 5.56 | .345 | 1.55 | 10.5 | 3.6 | 6.3 | 98.2 | 114 | 64 | 61 | 11 | 39 | 69 | 0 | 0 | 0 | 0 | 1 | 3 | 2 | 4.34 |
| SP | Buehrle, M.Buehrle, Mark # >> | 22 | 2001 | L | 67 | 25 | 25 | 9 | 12 | 4.50 | .325 | 1.42 | 10.1 | 2.6 | 6.0 | 170.0 | 191 | 90 | 85 | 27 | 50 | 114 | 4 | 0 | 0 | 0 | 14 | 4 | 4 | 4.68 |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 50 | 25 | 25 | 12 | 11 | 5.17 | .346 | 1.58 | 11.0 | 3.3 | 5.9 | 142.2 | 173 | 85 | 82 | 20 | 52 | 93 | 0 | 0 | 0 | 0 | 12 | 1 | 4 | 4.64 |
| RP | Mota, G.Mota, Guillermo >> | 30 | 2003 | R | 49 | 66 | 0 | 5 | 6 | 4.14 | .318 | 1.34 | 9.2 | 2.9 | 7.2 | 91.1 | 93 | 43 | 42 | 12 | 29 | 73 | 0 | 4 | 2 | 0 | 0 | 6 | 0 | 4.26 |
| RP | Hawkins, L.Hawkins, LaTroy >> | 30 | 2002 | R | 40 | 54 | 0 | 2 | 1 | 3.57 | .314 | 1.33 | 8.5 | 3.6 | 6.9 | 70.2 | 66 | 33 | 28 | 10 | 28 | 54 | 0 | 2 | 3 | 0 | 0 | 3 | 2 | 4.64 |
| RP | Stewart, S.Stewart, Scott >> | 27 | 2002 | L | 28 | 49 | 0 | 5 | 1 | 3.55 | .285 | 1.18 | 7.5 | 3.1 | 8.0 | 66.0 | 55 | 28 | 26 | 12 | 23 | 59 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 4.67 |