| SP | Santana, J.Santana, Johan † # $$ >> | 25 | 2004 | L | 100 | 19 | 19 | 9 | 5 | 3.76 | .272 | 1.11 | 7.2 | 2.8 | 10.5 | 129.1 | 103 | 55 | 54 | 14 | 40 | 151 | 2 | 0 | 0 | 2 | 13 | 2 | 2 | 3.05 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 86 | 18 | 18 | 2 | 9 | 6.22 | .365 | 1.68 | 11.4 | 3.9 | 9.2 | 105.2 | 133 | 77 | 73 | 17 | 45 | 107 | 0 | 0 | 0 | 0 | 5 | 4 | 0 | 4.47 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 81 | 18 | 18 | 8 | 10 | 5.66 | .340 | 1.49 | 11.1 | 2.3 | 7.6 | 105.0 | 129 | 69 | 66 | 22 | 27 | 89 | 1 | 0 | 0 | 0 | 8 | 6 | 0 | 4.97 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 17 | 17 | 6 | 6 | 5.49 | .346 | 1.57 | 10.2 | 3.9 | 7.2 | 103.1 | 117 | 63 | 63 | 15 | 45 | 82 | 0 | 0 | 0 | 0 | 8 | 2 | 0 | 4.67 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 68 | 17 | 17 | 5 | 7 | 4.45 | .305 | 1.30 | 9.2 | 2.5 | 7.2 | 119.1 | 122 | 59 | 59 | 20 | 33 | 95 | 1 | 0 | 0 | 0 | 8 | 2 | 4 | 4.47 |
| CL | Betancourt, R.Betancourt, Rafael $$ >> | 32 | 2007 | R | 87 | 28 | 0 | 4 | 4 | 4.13 | .295 | 1.26 | 9.3 | 2.3 | 9.0 | 32.2 | 33 | 15 | 15 | 4 | 8 | 32 | 0 | 13 | 3 | 0 | 0 | 0 | 0 | 3.38 |
| SU | Percival, T.Percival, Troy >> | 38 | 2007 | R | 84 | 29 | 0 | 0 | 1 | 4.34 | .298 | 1.24 | 8.7 | 2.5 | 7.1 | 29.0 | 28 | 14 | 14 | 2 | 8 | 23 | 0 | 0 | 5 | 0 | 0 | 1 | 0 | 3.24 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 88 | 40 | 0 | 0 | 4 | 4.32 | .290 | 1.20 | 7.7 | 3.3 | 5.7 | 41.2 | 35 | 21 | 20 | 7 | 15 | 26 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 5.12 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 55 | 15 | 0 | 1 | 1 | 6.05 | .348 | 1.57 | 11.0 | 3.1 | 6.1 | 58.0 | 71 | 39 | 39 | 13 | 20 | 39 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 5.71 |