| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 7 | 7 | 1 | 2 | 4.64 | .288 | 1.21 | 8.7 | 2.2 | 8.2 | 33.0 | 32 | 17 | 17 | 9 | 8 | 30 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 5.45 |
| SP | Weaver, J.Weaver, Jered # >> | 24 | 2006 | R | 83 | 6 | 6 | 2 | 2 | 5.08 | .350 | 1.54 | 10.8 | 3.0 | 7.4 | 39.0 | 47 | 25 | 22 | 12 | 13 | 32 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 6.59 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 68 | 6 | 6 | 0 | 2 | 7.82 | .355 | 1.60 | 11.8 | 2.8 | 4.4 | 35.2 | 46 | 32 | 31 | 14 | 11 | 17 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 8.34 |
| SP | Millwood, K.Millwood, Kevin >> | 28 | 2002 | R | 50 | 6 | 6 | 2 | 3 | 6.25 | .349 | 1.58 | 11.6 | 2.9 | 4.6 | 31.2 | 40 | 23 | 22 | 4 | 10 | 16 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 4.71 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 16 | 0 | 1 | 2 | 5.66 | .333 | 1.50 | 10.8 | 3.2 | 11.7 | 20.2 | 24 | 13 | 13 | 5 | 7 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.70 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 67 | 15 | 0 | 2 | 1 | 2.84 | .313 | 1.37 | 7.1 | 5.2 | 7.1 | 19.0 | 15 | 8 | 6 | 1 | 11 | 15 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.84 |
| RP | Mota, G.Mota, Guillermo >> | 30 | 2003 | R | 49 | 15 | 0 | 0 | 0 | 1.83 | .298 | 1.17 | 8.5 | 2.4 | 8.1 | 19.2 | 18 | 6 | 4 | 2 | 5 | 17 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 3.68 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 39 | 13 | 0 | 2 | 1 | 3.21 | .311 | 1.36 | 8.4 | 3.9 | 8.4 | 14.0 | 13 | 5 | 5 | 0 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.43 |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 39 | 10 | 0 | 1 | 2 | 4.18 | .360 | 1.69 | 11.0 | 4.7 | 7.4 | 23.2 | 28 | 12 | 11 | 1 | 12 | 19 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.48 |