| SP | Richard, J.Richard, J.R. † $ >> | 30 | 1980 | R | 93 | 17 | 17 | 8 | 6 | 2.34 | .274 | 1.13 | 6.1 | 4.1 | 9.5 | 119.0 | 80 | 31 | 31 | 12 | 54 | 126 | 1 | 0 | 0 | 1 | 13 | 1 | 3 | 3.58 |
| SP | Maddux, G.Maddux, Greg $ >> | 29 | 1995 | R | 90 | 17 | 17 | 8 | 3 | 3.98 | .271 | 1.09 | 7.8 | 2.1 | 6.3 | 117.2 | 101 | 52 | 52 | 16 | 27 | 82 | 3 | 0 | 0 | 2 | 9 | 3 | 1 | 4.15 |
| SP | Ryan, N.Ryan, Nolan † $$ >> | 44 | 1991 | R | 80 | 16 | 16 | 9 | 4 | 2.78 | .274 | 1.09 | 5.9 | 4.0 | 8.2 | 113.1 | 74 | 39 | 35 | 12 | 50 | 103 | 3 | 0 | 0 | 1 | 10 | 4 | 4 | 3.99 |
| SP | Tanana, F.Tanana, Frank # >> | 23 | 1976 | L | 73 | 16 | 16 | 8 | 6 | 3.91 | .276 | 1.12 | 7.9 | 2.2 | 7.3 | 117.1 | 103 | 51 | 51 | 21 | 28 | 95 | 9 | 0 | 0 | 1 | 9 | 3 | 1 | 4.50 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 66 | 16 | 16 | 6 | 8 | 4.11 | .312 | 1.31 | 9.2 | 2.6 | 8.8 | 96.1 | 98 | 46 | 44 | 18 | 28 | 94 | 0 | 0 | 0 | 0 | 10 | 5 | 4 | 4.51 |
| RP | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 48 | 0 | 4 | 0 | 1.37 | .229 | 0.87 | 4.5 | 3.3 | 10.6 | 46.0 | 23 | 7 | 7 | 2 | 17 | 54 | 0 | 7 | 0 | 0 | 0 | 1 | 1 | 2.39 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 86 | 53 | 0 | 1 | 0 | 3.93 | .304 | 1.25 | 8.2 | 3.2 | 10.9 | 34.1 | 31 | 16 | 15 | 4 | 12 | 41 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 3.35 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 81 | 35 | 0 | 1 | 1 | 5.16 | .270 | 1.08 | 6.2 | 3.7 | 11.5 | 29.2 | 20 | 17 | 17 | 7 | 12 | 37 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 4.93 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 21 | 0 | 1 | 3 | 4.24 | .333 | 1.46 | 5.9 | 7.4 | 10.6 | 23.1 | 15 | 15 | 11 | 2 | 19 | 27 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 4.39 |
| RP | Guardado, E.Guardado, Eddie >> | 33 | 2003 | L | 23 | 39 | 0 | 3 | 2 | 5.22 | .318 | 1.33 | 8.4 | 3.7 | 5.6 | 29.1 | 27 | 17 | 17 | 3 | 12 | 18 | 0 | 6 | 0 | 0 | 0 | 2 | 1 | 4.55 |