| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 27 | 27 | 11 | 10 | 3.72 | .287 | 1.21 | 7.6 | 3.3 | 8.6 | 193.1 | 163 | 85 | 80 | 27 | 70 | 184 | 0 | 0 | 0 | 0 | 16 | 1 | 4 | 4.02 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 26 | 26 | 11 | 11 | 5.73 | .310 | 1.34 | 9.5 | 2.6 | 9.3 | 172.2 | 181 | 116 | 110 | 50 | 50 | 178 | 2 | 0 | 0 | 0 | 8 | 2 | 7 | 5.62 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 25 | 25 | 11 | 6 | 4.09 | .300 | 1.25 | 8.4 | 2.9 | 6.3 | 165.0 | 154 | 84 | 75 | 26 | 53 | 116 | 0 | 0 | 0 | 0 | 13 | 5 | 3 | 4.70 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 62 | 24 | 24 | 10 | 9 | 4.29 | .315 | 1.37 | 9.2 | 3.2 | 6.9 | 161.2 | 164 | 79 | 77 | 24 | 58 | 123 | 0 | 0 | 0 | 0 | 15 | 1 | 3 | 4.51 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 55 | 0 | 3 | 4 | 3.76 | .329 | 1.47 | 9.8 | 3.4 | 9.5 | 55.0 | 60 | 23 | 23 | 7 | 21 | 58 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.69 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 75 | 40 | 0 | 2 | 0 | 5.26 | .335 | 1.49 | 8.3 | 5.4 | 9.2 | 37.2 | 34 | 22 | 22 | 7 | 22 | 38 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 5.27 |
| CL | Kimbrel, C.Kimbrel, Craig † $ >> | 24 | 2012 | R | 100 | 53 | 0 | 3 | 7 | 5.00 | .319 | 1.37 | 9.0 | 3.3 | 12.3 | 54.0 | 54 | 32 | 30 | 12 | 20 | 74 | 0 | 31 | 4 | 0 | 0 | 2 | 2 | 4.37 |